Protein Alignment Tdc2 and gadl1

DIOPT Version :10

• Sequence 1: NP_724489.1
• Gene: Tdc2 / 246620
• FlyBaseID: FBgn0050446
• Length: 637
• Species: Drosophila melanogaster
• Sequence 2: XP_012820293.1
• Gene: gadl1 / 733871
• XenbaseID: XB-GENE-5721903
• Length: 522
• Species: Xenopus tropicalis
• Alignment Length: 524
• Identity: 128/524 - (24%)
• Similarity: 212/524 - (40%)
• Gaps: 92/524 - (17%)

  Fly     1 MDSTEFRKRGMEMVEYICNYLETLNE---------RRVTPSVEPGYLRHLLPPEAPQEPEDWDQI 56
            :||:.    |.:.||.:  |...:||         ::|....||..|:.||........|..:::
 Frog    41 IDSSS----GEKFVEDV--YRILMNELVYKASDINQKVCEWQEPEQLKKLLDLNIKDNGEPHEKL 99

  Fly    57 MRDVEDKIMPGVTHWQHPRFHAYFPAGNSFPSILGDMLGDGIGCIGFSWAASPACTELETIVLDW 121
            ::..::.|...| ...||||.....||....|:....:.:.:....:::..||.....|..:|.
 Frog   100 LQLCKNVIKYSV-KTSHPRFFNQLYAGMDHYSLAARFITEALNPSVYTYEVSPVFILTEEAILK- 162

  Fly   122 LGKAIGLPDHFLALKEG----STGGGVIQTSASECVLVTMLAARAQALKRLKAQHPFVEEGHLLS 182
              |.|    .||..|||    |.||.|....|..             |.|.| ..|.:::..|.|
 Frog   163 --KMI----EFLGWKEGDGIFSPGGSVSNMYAVN-------------LARYK-YCPDIKQKGLSS 207

  Fly   183 --KLMAYCSKEAHSCVEKAAM--------ICFVKLRILEPDDDASLRGQTIYEAMEED----ELQ 233
              :|:.:.|:|.|..::|||.        :.|||      .||   ||:.|.|.:|..    :.:
 Frog   208 APRLVMFTSEECHYSMKKAAAFLGIGTENVYFVK------TDD---RGKMIPEELENQIQRAKKE 263

  Fly   234 GLVPFFVSTTLGTTGSCAFDNLPEIGKQLQRFPGVWLHVDAAYAGNSFICPELKPLLKGIEYADS 298
            ..|||.||.|.|||...|||.|.:|....::.. :|.||||::.|::.:..:.:..|.||..|||
 Frog   264 AAVPFLVSATSGTTVLGAFDPLDDIANICEKHK-LWFHVDASWGGSALMSQKYRKCLHGIHRADS 327

  Fly   299 FNTNPNKWLLTNFDCSTLWVRDR---IRLTSALVVDPLYLKHGYSDAAIDYRHWGVPLSRRFRSL 360
            ...||:|.|:....|..|.|||.   ::...:.....|:.:..:.|...|.....:..|||..:.
 Frog   328 VAWNPHKMLMAGIQCCALLVRDNSGLLKRCHSAEATYLFQQDKFYDVQYDTGDKSIQCSRRADAF 392

  Fly   361 KLWFVLRSYGISGLQHYIRHHIKLAKRFEELVLKDKRFEICNQVKLGLVCF---------RLKGS 416
            |.|.:.::.|.:||:..|...:.|.:.....:.|...||:..:.:....||         ..||.
 Frog   393 KFWMMWKALGTTGLEERINRALALTRYLASEIKKRDGFELLWEPEYANTCFWYIPPSFRNMEKGP 457

  Fly   417 D----------KLNEKLLSIINESGKLHMVPASVGDRY-IIRFCAVAQNATAEDIDYAWDIIVDF 470
            :          .:.|:::    :.|.:.:......|:. ..|...::...:.||:|:..|.|...
 Frog   458 EYWRKFSNVAPTIKERMM----KKGSMMVGYQPHRDKVNFFRHIVISPQVSREDMDFVLDEIERL 518

  Fly   471 ANEL 474
            ..:|
 Frog   519 GRDL 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tdc2	NP_724489.1	Pyridoxal_deC	35..414	CDD:395219	106/408 (26%)
gadl1	XP_012820293.1	GadA	76..521	CDD:439846	118/480 (25%)