Protein Alignment Tdc2 and SEPSECS

DIOPT Version :9

• Sequence 1: NP_724489.1
• Gene: Tdc2 / 246620
• FlyBaseID: FBgn0050446
• Length: 637
• Species: Drosophila melanogaster
• Sequence 2: XP_016863766.1
• Gene: SEPSECS / 51091
• HGNCID: 30605
• Length: 586
• Species: Homo sapiens
• Alignment Length: 552
• Identity: 111/552 - (20%)
• Similarity: 184/552 - (33%)
• Gaps: 194/552 - (35%)

  Fly    97 GIGCIGFSWAASP--ACTEL-----ETIVLDWLGKAIGLPDHFLALKEGSTGGGVIQTSASECVL 154
            |||..|...|..|  |.:.|     .::|||.: |..|:  |.:|                .|.:
Human   179 GIGRSGDISAVQPKAAGSSLLNKITNSLVLDII-KLAGV--HTVA----------------NCFV 224

  Fly   155 VTMLAARAQALKRLKAQHPFVEEGHLLSKLMAYCSKEAHSCVEKAAMICF---VKLRILEPDDDA 216
            |.|....:..|..|..:|...:     :|.:.:...:..||.:......|   |...:||.|:
Human   225 VPMATGMSLTLCFLTLRHKRPK-----AKYIIWPRIDQKSCFKSMITAGFEPVVIENVLEGDE-- 282

  Fly   217 SLRGQTIYEAMEEDELQGLVPFFVSTTLGTTGSCAFDNLPEIGKQL------QRFPGVWLHVDAA 275
             ||  |..:|:|. ::|.|.|..:.....|| ||....:|:..::|      ...|.:   |:.|
Human   283 -LR--TDLKAVEA-KVQELGPDCILCIHSTT-SCFAPRVPDRLEELAVICANYDIPHI---VNNA 339

  Fly   276 YAGNSFICPELKPLLKGIEYADSFNTNPNKWLLTNFDCSTLWVRDRIRLTSALVVDPLYLKHGYS 340
            |...|..|..|......:...|:|..:.:|    ||         .:.:..|::.       |::
Human   340 YGVQSSKCMHLIQQGARVGRIDAFVQSLDK----NF---------MVPVGGAIIA-------GFN 384

  Fly   341 DAAIDYRHWGVPLSRRF-------RSLKLWFVLRSYGISGLQHYIRHHIKLAKRFEELVLKDKRF 398
            |:.|.      .:|:.:       .||.:...|.|.|.:|.:       ||.|..:|:      |
Human   385 DSFIQ------EISKMYPGRASASPSLDVLITLLSLGSNGYK-------KLLKERKEM------F 430

  Fly   399 E-ICNQVKLGLVCFRLKGSDKLNEKLLSIINESGKLHMVPASVGDRYIIRFCAVAQNATAEDIDY 462
            . :.||:|        |.|:..||:||
Human   431 SYLSNQIK--------KLSEAYNERLL-------------------------------------- 449

  Fly   463 AWDIIVDFANELLEKEQHDELSEIMNRKKQDTLAQK------RSFFVRMVSDPKIYNPAINKAGT 521
                          ...|:.:|..|..|..|....|      ...|.|.||..::         .
Human   450 --------------HTPHNPISLAMTLKTLDEHRDKAVTQLGSMLFTRQVSGARV---------V 491

  Fly   522 PKLSMELPSPVVSRGSAPIIRTQSSVDHNSWISWPLAFLFNSNNE--EKGSNVSLRFRHLDTNVR 584
            |..||:..|....||         .:.|.:  ::|.|:| |:.:.  .|..:|.|..:.||..::
Human   492 PLGSMQTVSGYTFRG---------FMSHTN--NYPCAYL-NAASAIGMKMQDVDLFIKRLDRCLK 544

  Fly   585 PSSSRRNSGAGSSPSPENELDYVNVQQQQMEQ 616
            .....|        |.|::.:|...:...:|:
Human   545 AVRKER--------SKESDDNYDKTEDVDIEE 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tdc2	NP_724489.1	Pyridoxal_deC	35..414	CDD:278699	74/340 (22%)
SEPSECS	XP_016863766.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900