Protein Alignment Tdc2 and ddc

DIOPT Version :10

• Sequence 1: NP_724489.1
• Gene: Tdc2 / 246620
• FlyBaseID: FBgn0050446
• Length: 637
• Species: Drosophila melanogaster
• Sequence 2: NP_001011289.1
• Gene: ddc / 496742
• XenbaseID: XB-GENE-983285
• Length: 485
• Species: Xenopus tropicalis
• Alignment Length: 484
• Identity: 261/484 - (53%)
• Similarity: 354/484 - (73%)
• Gaps: 4/484 - (0%)

  Fly     1 MDSTEFRKRGMEMVEYICNYLETLNERRVTPSVEPGYLRHLLPPEAPQEPEDWDQIMRDVEDKIM 65
            |:::||||||.:||:|:.:|||.:..|:|.|.|||||||.|:|..||:|.|.:::|::|||..||
 Frog     1 MNASEFRKRGKDMVDYVADYLEQIESRQVFPDVEPGYLRPLIPDSAPEEGETYEEIIKDVERVIM 65

  Fly    66 PGVTHWQHPRFHAYFPAGNSFPSILGDMLGDGIGCIGFSWAASPACTELETIVLDWLGKAIGLPD 130
            ||||||..|.|.||||.|:|:|::|.|||...|||||||||:|||||||||::||||||.||||:
 Frog    66 PGVTHWHSPYFFAYFPTGSSYPALLADMLCGAIGCIGFSWASSPACTELETVMLDWLGKMIGLPE 130

  Fly   131 HFLALKEGSTGGGVIQTSASECVLVTMLAARAQALKRLKAQHPFVEEGHLLSKLMAYCSKEAHSC 195
            .|||..:|. ||||||.:|||..|:.:||||.:..:||:|::|.:.|..::|:::||.|.:|||.
 Frog   131 QFLAGNKGE-GGGVIQGTASEATLMALLAARTKVTRRLQAENPKLTEAEIVSRMVAYSSDQAHSS 194

  Fly   196 VEKAAMICFVKLRILEPDDDASLRGQTIYEAMEEDELQGLVPFFVSTTLGTTGSCAFDNLPEIGK 260
            ||:|.:|..|:::.:..|::...|||.:.:|:|||:.:||:|.|...|||||.|||||||.|:|
 Frog   195 VERAGLISGVRMKKIPSDENFVARGQALKKALEEDKAEGLIPIFFCATLGTTNSCAFDNLLELG- 258

  Fly   261 QLQRFPGVWLHVDAAYAGNSFICPELKPLLKGIEYADSFNTNPNKWLLTNFDCSTLWVRDRIRLT 325
            .:.....:|:|:||||||::|||||.:.|:||||:|||||.||:||||.||||||.||:.|..|.
 Frog   259 PVCNAENIWMHIDAAYAGSAFICPEFRYLMKGIEFADSFNFNPHKWLLVNFDCSTFWVKKRSDLI 323

  Fly   326 SALVVDPLYLKHGYSDAAI--DYRHWGVPLSRRFRSLKLWFVLRSYGISGLQHYIRHHIKLAKRF 388
            .|..:||:||::...::.:  |||||.:||.|||||||||||.|.||:.|||.:||.|:.||..|
 Frog   324 GAFKMDPVYLQYDQQESGLVTDYRHWQIPLGRRFRSLKLWFVFRIYGVKGLQVHIRKHVGLAHEF 388

  Fly   389 EELVLKDKRFEICNQVKLGLVCFRLKGSDKLNEKLLSIINESGKLHMVPASVGDRYIIRFCAVAQ 453
            .|.|.||.:||||..|.|||||||||||::||:.||..||.|.|:|:||..:||.:::||...|:
 Frog   389 LECVKKDDQFEICAPVILGLVCFRLKGSNELNKALLQKINNSKKIHIVPCCLGDTFVLRFAVCAR 453

  Fly   454 NATAEDIDYAWDIIVDFANELLEKEQHDE 482
            ...:..|.:||..|.:...|||..|:..:
 Frog   454 TVESSHIQFAWKHIKELTTELLNNEEQQK 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tdc2	NP_724489.1	Pyridoxal_deC	35..414	CDD:395219	215/380 (57%)
ddc	NP_001011289.1	Pyridoxal_deC	35..414	CDD:395219	215/380 (57%)