Protein Alignment Tdc2 and hdl-2

DIOPT Version :9

• Sequence 1: NP_724489.1
• Gene: Tdc2 / 246620
• FlyBaseID: FBgn0050446
• Length: 637
• Species: Drosophila melanogaster
• Sequence 2: NP_501539.3
• Gene: hdl-2 / 182464
• WormBaseID: WBGene00006409
• Length: 611
• Species: Caenorhabditis elegans
• Alignment Length: 547
• Identity: 117/547 - (21%)
• Similarity: 230/547 - (42%)
• Gaps: 122/547 - (22%)

  Fly     5 EFRKRGMEMVEYICNYLETLNERRVTPSVEPGYLR-HLLPPEAPQEPEDWDQIMRDVEDKIMPGV 68
            ||.|....:|::|.:|.:..:::.|.|..:....| |:   :.|::.|:..:|::|:::.::|.:
 Worm   118 EFIKCMSLVVQFINDYFDESHKQPVIPENDVNSSRIHV---KVPEKAEELTEILKDLKEIVIPNI 179

  Fly    69 THWQHPRFHAYFPAGNSFPSILGDMLGDGI-GCIGFSWAASPACTELETIVLDWLGKAIGLPDHF 132
            .|..|||:||.| ||.|    |.|::...| ..:|....:||....:|.|:..||..::.:|...
 Worm   180 CHTHHPRYHAKF-AGKS----LADLVASTISAALGHDVNSSPIIESIERIICKWLSTSMAIPQIK 239

  Fly   133 LALKE-GSTGGGVIQTSASECVLVTMLAARAQALKRLKAQHPFVEEGHLLSK---LMAYCSKEAH 193
            .:|.| ....|.|..|...  |.::::....:..::       .:.|...||   .:.|||.::.
 Worm   240 SSLGELRDPIGTVFYTPCD--VFISVIRHAIEKFEK-------TDSGKERSKNADYIVYCSDDSQ 295

  Fly   194 SCVEKAAMICFVKLR--ILEPDDDASLRGQTIYEAMEEDELQGLVPFFVSTTLGTTGSCAFDNLP 256
            ..:::..:.|.||||  |.:..:.:.:....:.:.||:|..:|..|..:....|:....|.|.:.
 Worm   296 VPLKEPCISCRVKLRKVITDEKNGSGMTSANLLKQMEKDIARGFTPLVIIANYGSANIAANDEIW 360

  Fly   257 EIGKQLQRFPGVWLHVDAAYAGNSFICPELKPLLKGIEYADSFNTNPNKWLLT-----NFDCSTL 316
            :: ..:.|...:|||:||:|||    |          |:.||.:.|....|::     :..||:|
 Worm   361 DL-VTVSRSKKIWLHLDASYAG----C----------EWLDSNSRNNVHALISEVHSVHITCSSL 410

  Fly   317 ----------WVRDRIRLTSALVVDPLYLKHGYSDAAIDYRHWGVPLSRRFRSLKLWFVLRSYGI 371
                      |..:::.|..|.:   ||.:|                     .::||.::|.:||
 Worm   411 FPYSGRISVVWSCEKLELDGAKI---LYGEH---------------------PIRLWILIRLHGI 451

  Fly   372 SGLQHYIRHHIKLAKRFEELVLKDKR-FEICNQVKLGLVCFRLKGSDKLNEKLLSIINESGKLHM 435
            ..::..::..|.|...|.|.:....: ||:.:..:.|:..|:.|     |:|:.....::.|:
 Worm   452 RSIREAVKRKIILGNAFSERMSHHSQLFEMHHTNEHGVTVFQYK-----NKKIKDRTEDTNKI-- 509

  Fly   436 VPASVGDRYIIRFCAVAQNATAEDIDYAWDIIVDFANELLEK---------------------EQ 479
              .|:...|::         .:..:.::   ||.|..::|.|                     ..
 Worm   510 --TSMFHNYLV---------LSSTLKFS---IVSFHGKVLIKSVVNYGRCNLSIMDESVSTLVNS 560

  Fly   480 HDELSEIMNRKKQDTLAQKRSFFVRMV 506
            .||..|.:.:||:......::.|..|:
 Worm   561 VDEFEEALKKKKKIVCETPKNEFCEMI 587

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tdc2	NP_724489.1	Pyridoxal_deC	35..414	CDD:278699	91/402 (23%)
hdl-2	NP_501539.3	AAT_I	125..527	CDD:302748	102/478 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11999
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910