Protein Alignment Tdc2 and hdl-1

DIOPT Version :9

• Sequence 1: NP_724489.1
• Gene: Tdc2 / 246620
• FlyBaseID: FBgn0050446
• Length: 637
• Species: Drosophila melanogaster
• Sequence 2: NP_502265.2
• Gene: hdl-1 / 178129
• WormBaseID: WBGene00001839
• Length: 905
• Species: Caenorhabditis elegans
• Alignment Length: 586
• Identity: 220/586 - (37%)
• Similarity: 341/586 - (58%)
• Gaps: 60/586 - (10%)

  Fly     1 MDSTEFRKRGMEMVEYICNYLETLNERRVTPSVEPGYLRHLLPPEAPQEPEDWDQIMRDVEDKIM 65
            |...:||....::|:|:....|::...|.:|:::||||:.||||:|||:.||.|.|:.|....|:
 Worm   343 MSRDQFRNAAKKVVDYLMKQDESIRAARCSPALKPGYLKALLPPKAPQKAEDIDDILEDYHKLIV 407

  Fly    66 PGVTHWQHPRFHAYFPAGNSFPSILGDMLGDGIGCIGFSWAASPACTELETIVLDWLGKAIGLPD 130
            ||::|..||.||:::||||||..:|.|:||..||..||.|.::||.||||.:::||||:.:.||.
 Worm   408 PGLSHSSHPNFHSFYPAGNSFHCLLADLLGGHIGDAGFYWTSNPALTELEVLMMDWLGEMMALPK 472

  Fly   131 HFLALKEGSTGGGVIQTSASECVLVTMLAARAQALKRLKAQHPFVEEGHLLSKLMAYCSKEAHSC 195
            .||...|.|.|||.:|.|.:|...:.::|||...::|:|.:...:....:|::|:||.|.:|...
 Worm   473 EFLLFPEASRGGGCMQRSDTESNFLVLVAARTDMIRRMKQRDKRLRSSDILARLVAYTSSDARRS 537

  Fly   196 V--EKAAMICFVKLRILEPDDDASLRGQTIYEAMEEDELQGLVPFFVSTTLGTTGSCAFDNLPEI 258
            :  :.||.:..||:|:|..|.:..|||.|::.|:..|..:||:||||....||:|.|:||:|.|:
 Worm   538 IKMKMAAEVAMVKMRVLPTDQNFILRGDTLHAAIMADIERGLIPFFVGANFGTSGPCSFDHLHEL 602

  Fly   259 GKQLQRFPGVWLHVDAAYAGNSFICPELKPLLKGIEYADSFNTNPNKWLLTNFDCSTLWVRDRIR 323
            | .:.|..|.||||||||||.:.||||::.|::||::||||.|.|:|.::...|...||||||.:
 Worm   603 G-PVCREHGTWLHVDAAYAGTALICPEIRGLMRGIDWADSFCTTPSKLIIAVCDVCCLWVRDRHK 666

  Fly   324 LTSALVVDPLYLKHGYSDAAIDYRHWGVPLSRRFRSLKLWFVLRSYGISGLQHYIRHHIKLAKRF 388
                       |:|...:...|....|:|.|:|..:||:||::||:|:..||:.||.||:|.:..
 Worm   667 -----------LQHASLENHPDLPFKGLPTSQRVGALKIWFMIRSFGVENLQNQIREHIRLGQVM 720

  Fly   389 EELVLKDKRFEICNQVKLGLVCFRLKGSDKLNEKLLSIINESGKLHMVPASVGDRYIIRFCAVAQ 453
            .:::.||.|||:||:|.:||:|||.|.:|..|:.||...||:|.:.:....:.::::||.|..:.
 Worm   721 TKILQKDLRFEVCNKVVMGLICFRAKSNDMFNKALLYRCNETGNVSLASCVLQNKFVIRMCINSP 785

  Fly   454 NATAEDIDYAWDIIVDFANE--LLEKEQHDELSEIMNRKKQDTLAQKRSFFVRMVSDP-KIYN-- 513
            ..:.||:|.|:.:|   .||  :|:..|:  ..|:||:.:.:|       |:|   || ||::
 Worm   786 KCSEEDLDSAYKLI---CNEYDILKPFQY--RIEVMNQAELET-------FIR---DPAKIHSSA 835

  Fly   514 ------PAINK-------------------AGTPKLSMELPSPVVSRGSAPIIRTQSSVDHNSWI 553
                  |.:|.                   |..|..|.:.|. |.::|..|.....||...||.|
 Worm   836 EVSRRFPVVNPLEPCRSLAQISSQMHTAEYADPPGKSNKSPQ-VAAKGELPSAAPPSSRTPNSDI 899

  Fly   554 S 554
            |
 Worm   900 S 900

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tdc2	NP_724489.1	Pyridoxal_deC	35..414	CDD:278699	167/380 (44%)
hdl-1	NP_502265.2	Pyridoxal_deC	377..746	CDD:278699	167/380 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D223497at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11999
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920