Protein Alignment Tdc2 and gad1a

DIOPT Version :10

• Sequence 1: NP_724489.1
• Gene: Tdc2 / 246620
• FlyBaseID: FBgn0050446
• Length: 637
• Species: Drosophila melanogaster
• Sequence 2: XP_002663350.1
• Gene: gad1a / 100329827
• ZFINID: ZDB-GENE-070912-472
• Length: 591
• Species: Danio rerio
• Alignment Length: 505
• Identity: 125/505 - (24%)
• Similarity: 216/505 - (42%)
• Gaps: 69/505 - (13%)

  Fly    11 MEMVEYICNYLETLNERRVTPSVEPGYLRHLLPP------EAPQEPEDWDQIMRDVEDKIMPGVT 69
            :|:||.:.||:....:|. |..::..:...||..      |...:||..:||:.|..|.:..||
Zfish   115 LEVVEILTNYVRKTFDRS-TKVLDFHHPHQLLEGMEGFNLELCDQPESLEQILVDCRDTLKYGV- 177

  Fly    70 HWQHPRFHAYFPAGNSFPSILGDMLGDGIGCIGFSWAASPACTELETIVLDWLGKAIGLPDHFLA 134
            ...||||.....:|.....:.|:.|........|::..:|....:|.:.|..:.:.:|.|:
Zfish   178 RTGHPRFFNQLSSGLDIIGLAGEWLTSTANTNMFTYEIAPVFVLMEQLTLKKMREIVGWPN---- 238

  Fly   135 LKEGSTGGGVIQTSASECVLVTMLAARAQALKRLK----AQHPFVEEGHLLSKLMAYCSKEAHSC 195
                ..|.|:.....:...:.:::.||.:....:|    |..|         :|:.:.|:.:|..
Zfish   239 ----GEGDGIFSPGGAISNMYSVMVARYKHYPEIKIKGMAAAP---------RLVLFTSEHSHYS 290

  Fly   196 VEKA-AMICF--VKLRILEPDDDASLRGQTIYEAME----EDELQGLVPFFVSTTLGTTGSCAFD 253
            ::|| |::.|  ..|.:|..|:    ||:.|...:|    :.:.:|.||.||:.|.|:|...|||
Zfish   291 IKKASAVLGFGTENLILLRTDE----RGRVIPADLEAKVIDAKQKGFVPMFVNATAGSTVYGAFD 351

  Fly   254 NLPEIGKQLQRFPGVWLHVDAAYAGNSFICPELKPLLKGIEYADSFNTNPNKWLLTNFDCSTLWV 318
            .:.||....::: .:|||||.|:.|...:..:.|..|.|||.|:|...||:|.:.....||.:.|
Zfish   352 PINEIADICEKY-NMWLHVDGAWGGGLLMSRKHKHKLSGIERANSVTWNPHKMMGVPLQCSAILV 415

  Fly   319 RDR--IRLTSALVVDPLYLKHGYSDAAIDYRHWGVPLSRRFRSLKLWFVLRSYGISGLQHYIRHH 381
            |::  ::..:::....|:......|...|.....:...|.....|.|.:.:|.|.:|.:.:|...
Zfish   416 REKGLLQGCNSMCAGYLFQPDKQYDVTYDTGDKAIQCGRHVDIFKFWLMWKSKGTTGFEKHIDRC 480

  Fly   382 IKLAKRFEELVLKDKRFEICNQVKLG-----LVCF-------RL--KGSDKLNE------KLLSI 426
            ::|:   |.|..|.|..|....|..|     .|||       ||  .|.:|.:.      |:.::
Zfish   481 LELS---EYLYHKIKNREGYEMVFQGEPQHTNVCFWYIPPSLRLLPDGEEKRHRLHKVAPKIKAL 542

  Fly   427 INESGKLHMVPASVGDRYIIRFCAVAQN--ATAEDIDYAWDIIVDFANEL 474
            :.|.|...:.....|:: :..|..|..|  .|..|||:..|.|.....:|
Zfish   543 MMECGTTMVGYQPQGEK-VNFFRMVVSNPAVTRSDIDFLIDEIERLGQDL 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tdc2	NP_724489.1	Pyridoxal_deC	35..414	CDD:395219	102/411 (25%)
gad1a	XP_002663350.1	Pyridoxal_deC	141..515	CDD:395219	100/399 (25%)