Protein Alignment Tdc2 and gad1.2

DIOPT Version :10

• Sequence 1: NP_724489.1
• Gene: Tdc2 / 246620
• FlyBaseID: FBgn0050446
• Length: 637
• Species: Drosophila melanogaster
• Sequence 2: XP_012819752.1
• Gene: gad1.2 / 100145511
• XenbaseID: XB-GENE-5830282
• Length: 554
• Species: Xenopus tropicalis
• Alignment Length: 509
• Identity: 121/509 - (23%)
• Similarity: 210/509 - (41%)
• Gaps: 79/509 - (15%)

  Fly    11 MEMVEYICNYLETL--NERRVTPSVEPGYLRHLLPP---EAPQEPEDWDQIMRDVEDKIMPGVTH 70
            :|::..:.|:::..  .|.:|.....|..|...|..   |...:||..:||:.|..|.:...: .
 Frog    78 IEVLRILLNHIKKTYDGESKVLDFHHPHQLLEGLEGFNLELSDQPEPLEQILVDCSDTLKYSI-K 141

  Fly    71 WQHPRFHAYFPAGNSFPSILGDMLGDGIGCIGFSWAASPACTELETIVLDWLGKAIGLPDHFLAL 135
            ..|||:......|.....:.|:.|........|::..:|....:|.|||..:.:.||..:
 Frog   142 TGHPRYFNQLSCGLDIIGLAGEWLTATANTNMFTYEIAPVFIIMEEIVLKKMQEIIGWGE----- 201

  Fly   136 KEGSTGGGVIQTSASECVLVTMLAARAQALKRLKAQHPFVEEGHLLSKLMAYCSKEAHSCVEKAA 200
               :...|:.....:...|.::.|||.:....:|.:....     |.:::.:.|:::|...:||:
 Frog   202 ---NEADGIFSPGGTISNLYSLQAARYKYFPMVKTKGMAA-----LPQIVIFTSEQSHYSFKKAS 258

  Fly   201 MICFV---KLRILEPDDDASLRGQTIYEAMEEDEL----QGLVPFFVSTTLGTTGSCAFDNLPEI 258
            .|..:   .:..::.|:    ||:.|...:|:..|    ||..||:||.|.|||...|||.|..|
 Frog   259 AILGIGTDNVIAIKCDE----RGKMIPSDLEDKILKAKRQGQHPFYVSATAGTTVYGAFDPLITI 319

  Fly   259 GKQLQRFPGVWLHVDAAYAGNSFICPELKPLLKGIEYADSFNTNPNKWLLTNFDCSTLWVRDR-- 321
            ....:|: |:|:|||||:.|...:..:.:..:.|||.|:|...||:|.:.....||.:.:|.:
 Frog   320 ADICKRY-GLWMHVDAAWGGGLLLSKKHRYKMNGIERANSVTWNPHKIMGVPLQCSAILIRQKGL 383

  Fly   322 IRLTSALVVDPLYLKHGYSDAAIDYRHWGVPLSRRFRSLKLWFVLRSYGISG----------LQH 376
            ::..:....|.|:......|.|.|.....:...|.....|||.:.::.|..|          |..
 Frog   384 LQACNQQCADYLFQMDKPYDTAYDTGDKTIQCGRHVDIFKLWLMWKAKGSCGFELQINRCLELSE 448

  Fly   377 YIRHHIKLAKRFEELVLKDKRFEICNQVKLGLVCF------------------RLKGSDKLNEKL 423
            |:.:.::....| |||.:||. |..|      |||                  ||   .|:..::
 Frog   449 YLYNKLQSKSNF-ELVFRDKP-EYTN------VCFWYIPPSLEHVPRDKEWKARL---HKIAPQI 502

  Fly   424 LSIINESGKLHMVPASVGDRYIIRFCAVAQNATAEDIDYAWDIIVDFANELLEK 477
            .:.:.|.|.:.:.....||:... |..|..|..::..|      |||..|.:|:
 Frog   503 KARMMEEGTVMVSYQPQGDKPNF-FRMVFSNPASKKSD------VDFLLEEIER 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tdc2	NP_724489.1	Pyridoxal_deC	35..414	CDD:395219	102/418 (24%)
gad1.2	XP_012819752.1	Pyridoxal_deC	104..478	CDD:395219	101/400 (25%)