DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Opbp and Zfp280b

DIOPT Version :9

Sequence 1:	NP_724479.1	Gene:	Opbp / 246618	FlyBaseID:	FBgn0050443	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	NP_803426.2	Gene:	Zfp280b / 64453	MGIID:	1927865	Length:	534	Species:	Mus musculus

Alignment Length:	405	Identity:	91/405 - (22%)
Similarity:	141/405 - (34%)	Gaps:	93/405 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    90 PLWELVEEVPANVKAEKDQNEPSNSDRYFCYDCHSIFENRNKAEEHICPRAESGGS--------- 145
            ||.|      ::.::...|..||:|.:     |.|.....:.:|......|.|||.
Mouse   127 PLSE------SDYRSSSPQVVPSSSSK-----CCSPLVTLSSSENSPVKAALSGGDLNENLYVSK 180

  Fly   146 -----SQQDGDAKAPVRRKLAS------------VSARTGPRDASSVISCGICNTVFSSEKFLKF 193
                 :.|..|....:...|:|            :..||...||.:.:|..:
Mouse   181 CHFSINPQRPDHSIEIVEPLSSALPPSGTFHTSNMQQRTPSFDAPNSLSRLV------------- 232

  Fly   194 HMRIHENRAPKSIQDALPIGAHQQYSELDQ--FYCEICNKSFDE-----TLLT------VHK--- 242
                  |.||.|...|.|    :|.|.|.:  |......::||.     |||.      .:|
Mouse   233 ------NGAPPSEDSAHP----RQDSGLAEADFSSPASQETFDPKKGSLTLLLSDFYYGQYKGDG 287

  Fly   243 QMHQQESSEIMCSICNRKFENEVTYQMHQKIHEKPRDSESSRKLAQRTSLDKEKPGFPCQYCERV 307
            :..|:..:...|..|.:..:| |.:..|.|.|         .:|.::.|.|..:....|..|.|.
Mouse   288 KPEQKTHTTFKCPSCLKALKN-VKFMNHTKHH---------LELERQGSEDAWESHTTCLRCHRQ 342

  Fly   308 FTRPFEKVKH-ERVHTGEKP-YACEVCGKTFRVSYSLTLHLRTH--TNIRPYVCTVCNKRFKSH- 367
            |..||:...| :||||...| ..|::|..:|.....|..|::.:  ....||||.||..|....
Mouse   343 FDSPFQLECHIDRVHTSPDPSVVCKICELSFETDQVLLQHMKDNHKPGEMPYVCQVCKYRSSGFA 407

  Fly   368 QVYSHHLRIHSSERQFSCDACPKTFRTSVQLYAHKNTH--TKPYRCAVCNRPFSSMYAVKNHMQT 430
            .|.:|..:.|.:.:...|..|.|.|:|.:....|...|  ...::|:.|...|.:......|...
Mouse   408 DVETHFTKCHVNTKNLLCPFCLKIFKTGMPYMCHYRGHWERSGHQCSKCRLQFLTFKEKMEHKTQ 472

  Fly   431 HKEISSKGSVGSGTP 445
            ..::..|.....|.|
Mouse   473 CHQMFKKPKQLEGLP 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Opbp	NP_724479.1	C2H2 Zn finger	254..274	CDD:275368	6/19 (32%)
		C2H2 Zn finger	301..321	CDD:275368	8/20 (40%)
		zf-H2C2_2	316..336	CDD:290200	8/21 (38%)
		C2H2 Zn finger	329..349	CDD:275368	5/19 (26%)
		zf-H2C2_2	341..366	CDD:290200	9/26 (35%)
		C2H2 Zn finger	357..377	CDD:275368	6/20 (30%)
		C2H2 Zn finger	385..405	CDD:275368	6/19 (32%)
		C2H2 Zn finger	411..431	CDD:275368	4/19 (21%)
Zfp280b	NP_803426.2	DUF4195	53..221	CDD:404681	20/104 (19%)
		C2H2 Zn finger	336..357	CDD:275368	8/20 (40%)
		C2H2 Zn finger	366..387	CDD:275368	5/20 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910