DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Opbp and CG6791

DIOPT Version :9

Sequence 1:	NP_724479.1	Gene:	Opbp / 246618	FlyBaseID:	FBgn0050443	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	NP_650090.1	Gene:	CG6791 / 41391	FlyBaseID:	FBgn0037918	Length:	1243	Species:	Drosophila melanogaster

Alignment Length:	732	Identity:	134/732 - (18%)
Similarity:	217/732 - (29%)	Gaps:	280/732 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 EDGDLSGGALQQEFLYCESCGNVYEDTESYDRAHGPQAGCCTGASGELDFIEEVA--------ED 73
            |:|:...|..:            .||:|.|             .:|..||:.:.|        :|
  Fly    16 EEGEAESGVAE------------LEDSEQY-------------GNGNDDFLGDTAILDSGDAIDD 55

  Fly    74 CISEEVGEEDIVYADVPLWELVEEVPANVKAEKDQNEPS-NSDRYFCYDCHSIFENRNKAEEHIC 137
            .:..|..|.             ||.....|..|:..:|. :.|..|.::...|.:........:.
  Fly    56 LLDAEEDER-------------EEEDDYEKNSKEPKQPDPDDDALFDFNMEPIVDIAEPQRPSLA 107

  Fly   138 PRAESGGSSQQDGDAKAPVRR----------KLA---SVSARTGPRDASS------------VIS 177
            |   :|..|||   .:.|::|          :|.   ||...|...:|:.            |..
  Fly   108 P---AGPMSQQ---VRPPMQRHSFPGAGGRPRLGSGLSVRPTTSQINATDENGVPINYELGVVYI 166

  Fly   178 CGICNTVFSSEKFLKFHM-RIHENRAPKSIQDALPIGAHQQYSELDQFY--CEICNKSF----DE 235
            |..|...|..:...|.|| .||:....:.:          .::.||:.|  |..|||..    .|
  Fly   167 CPACGGEFRQQDHWKRHMNHIHKYNTLRGL----------NFTPLDKLYQRCRECNKRIAMHSRE 221

  Fly   236 TLLTVHKQMHQQESSEIMCSICNRKFENEVTYQMH-QKIH------------------EKPRDSE 281
            .||. ||..|..... ..|.||.|:::......:| :.:|                  .:.|:|.
  Fly   222 NLLK-HKFTHLPFRC-TKCYICKREYKYRQDLMVHLRMVHCDEVVAMMREGYNAAGRKTRVRESR 284

  Fly   282 SSRKLAQRTSLDKEKPGFPCQYCERVFTR-----------------PFEKVKHERVHTGEKPYAC 329
            :.:.|.:::..:.:..|   :..:|:..|                 ..|:|..::..|......|
  Fly   285 TEQLLREKSFRENDDLG---EESDRIEVRNELLEPDADESGTQEQTVSEEVSKKKAGTRGAAELC 346

  Fly   330 EVCGKTFRVSYSLTLHLRTHTNIRPYVCTVCNKRFKSHQVYSHH------------LRIHSSERQ 382
            |        .|   :|         |:|..|.....:|..:|.|            |...|.:.|
  Fly   347 E--------DY---IH---------YMCPDCGTDCDTHAQWSQHIEFVHDYVSRRGLNFRSVDMQ 391

  Fly   383 FSCDACPK--TFRTSVQLYAHKNTH-TKP--YRCAVCNRPFSSMYAVKNH-MQTHK--------- 432
            ..|..|.|  |..|...|.|||.:| ::|  .||.:|.:.::....:..| :|.|.
  Fly   392 MQCLECKKIVTPNTIKSLRAHKFSHLSQPEWLRCKLCYKGYTDHQEIIRHLLQQHHMDTLMSEDA 456

  Fly   433 -----------EISSKGSVGSG----------TPNIKSAATSKSQAAG--------KFYCNTCGA 468
                       |....|..|:|          :|..:.|.....:.:.        .:.|..||.
  Fly   457 EEEDGDAPSAIEDECDGDNGNGEGNGAPLDEDSPYFEDAPRRGGRISSDDIFEPHIDYLCPQCGK 521

  Fly   469 EYARLFALRLHMKSAHG----------LVEEQENPATSTD------------------------- 498
            |:......|.|:..||.          ::.|::...|..|
  Fly   522 EFIEKKHWRTHVVMAHSMNDLSKLNFEMINERQLKCTECDKIITNAYGIQNAQQHRITHLPFKAY 586

  Fly   499 ----AAHVAETDDSE---------------------TAVLIAAAEADAAYINAVVNDVDIVGTVP 538
                ..|.:.||...                     .|.::..|:.....|..|.|:
  Fly   587 ARCRKCHKSYTDRKGLVKHLATHHRVGWPRKLSGGCPAPILTPAKQPRKQIVTVANE-------- 643

  Fly   539 TYEECVVFDVDNFHSEE 555
            |||...:.|||....||
  Fly   644 TYEIIYLDDVDQGGMEE 660

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Opbp	NP_724479.1	C2H2 Zn finger	254..274	CDD:275368	5/20 (25%)
		C2H2 Zn finger	301..321	CDD:275368	4/36 (11%)
		zf-H2C2_2	316..336	CDD:290200	3/19 (16%)
		C2H2 Zn finger	329..349	CDD:275368	4/19 (21%)
		zf-H2C2_2	341..366	CDD:290200	4/24 (17%)
		C2H2 Zn finger	357..377	CDD:275368	6/31 (19%)
		C2H2 Zn finger	385..405	CDD:275368	9/21 (43%)
		C2H2 Zn finger	411..431	CDD:275368	4/20 (20%)
CG6791	NP_650090.1	C2H2 Zn finger	167..188	CDD:275368	6/20 (30%)
		C2H2 Zn finger	208..230	CDD:275368	9/22 (41%)
		C2H2 Zn finger	235..256	CDD:275368	5/21 (24%)
		C2H2 Zn finger	516..532	CDD:275368	5/15 (33%)
		C2H2 Zn finger	557..580	CDD:275368	2/22 (9%)
		C2H2 Zn finger	589..609	CDD:275368	3/19 (16%)
		COG5236	<939..>1096	CDD:227561
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100