DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Opbp and Zfp143

DIOPT Version :9

Sequence 1:	NP_724479.1	Gene:	Opbp / 246618	FlyBaseID:	FBgn0050443	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	NP_001012169.2	Gene:	Zfp143 / 361627	RGDID:	1305662	Length:	638	Species:	Rattus norvegicus

Alignment Length:	355	Identity:	100/355 - (28%)
Similarity:	147/355 - (41%)	Gaps:	82/355 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   279 DSESSRKL-------AQRTSLDKEKPG---FPCQY--CERVFTRPFEKVKHERVHTGEKPYACE- 330
            ::|..:|:       |.|.:...::.|   |.|:|  |.:::|.......|||.|||::||.||
  Rat   207 ENEQEKKMQIVLQGHATRVTPKSQQSGEKAFRCKYDGCGKLYTTAHHLKVHERSHTGDRPYQCEH 271

  Fly   331 -VCGKTFRVSYSLTLHLRTHTNIRPYVCTV--CNKRFKSHQVYSHHLRIHSSERQFSC--DACPK 390
             .|||.|...|.|..|.||||..:||.|:.  |.|.||:......|:|.|:.||.|.|  :.|.:
  Rat   272 SGCGKAFATGYGLKSHFRTHTGEKPYRCSEDNCTKSFKTSGDLQKHIRTHTGERPFKCPIEGCGR 336

  Fly   391 TFRTSVQLYAHKNTHT--KPYRCAV--CNRPFSSMYAVKNHMQTHKEISSKGSVGSGTPNIKSAA 451
            :|.||.....|..|||  :||.|..  |.|.|:|....|||::.|  ...|..|.: .|......
  Rat   337 SFTTSNIRKVHIRTHTGERPYYCTEPGCGRAFASATNYKNHVRIH--TGEKPYVCT-VPGCDKRF 398

  Fly   452 TSKSQA---------AGKFYCNTCGAEYARLFALRLHMKSAHG----LVEEQE------------ 491
            |..|..         :..:.||.||..|.::..|.:|.::||.    :.||||
  Rat   399 TEYSSLYKHHVVHTHSKPYNCNHCGKTYKQISTLAMHKRTAHNDTEPIEEEQEAFFEPPPGQGDD 463

  Fly   492 ---------------NPATSTDAAHVAETDDSETAVLIAAAEADAAYINAVVNDVDIVG------ 535
                           ....||..|.|.::..|:...||  ::....::|....|:..:|
  Rat   464 VLKGSQITYVTGVEGEDIVSTQVATVTQSGLSQQVTLI--SQDGTQHVNISQADMQAIGNTITMV 526

  Fly   536 -------TVPTYEECVVFDVDNFHSEEVIT 558
                   ||||::  .|......||..::|
  Rat   527 TQDGTPITVPTHD--AVISSAGTHSVAMVT 554

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Opbp	NP_724479.1	C2H2 Zn finger	254..274	CDD:275368
		C2H2 Zn finger	301..321	CDD:275368	7/21 (33%)
		zf-H2C2_2	316..336	CDD:290200	13/21 (62%)
		C2H2 Zn finger	329..349	CDD:275368	10/21 (48%)
		zf-H2C2_2	341..366	CDD:290200	12/26 (46%)
		C2H2 Zn finger	357..377	CDD:275368	7/21 (33%)
		C2H2 Zn finger	385..405	CDD:275368	6/21 (29%)
		C2H2 Zn finger	411..431	CDD:275368	8/21 (38%)
Zfp143	NP_001012169.2	SFP1	<207..292	CDD:227516	29/84 (35%)
		C2H2 Zn finger	239..261	CDD:275368	7/21 (33%)
		COG5048	<251..424	CDD:227381	62/175 (35%)
		C2H2 Zn finger	269..291	CDD:275368	10/21 (48%)
		C2H2 Zn finger	299..321	CDD:275368	7/21 (33%)
		C2H2 Zn finger	329..351	CDD:275368	6/21 (29%)
		C2H2 Zn finger	359..381	CDD:275368	8/21 (38%)
		C2H2 Zn finger	389..411	CDD:275368	3/22 (14%)
		C2H2 Zn finger	419..438	CDD:275368	7/18 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000