DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Opbp and CG43347

DIOPT Version :9

Sequence 1:	NP_724479.1	Gene:	Opbp / 246618	FlyBaseID:	FBgn0050443	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	NP_001138185.2	Gene:	CG43347 / 31991	FlyBaseID:	FBgn0263072	Length:	2684	Species:	Drosophila melanogaster

Alignment Length:	616	Identity:	129/616 - (20%)
Similarity:	196/616 - (31%)	Gaps:	212/616 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 SYDRAHGPQAGCCTGASGE-LDFIEEVAEDCISEEVGEEDIVYADVPLWELVEEVPANVKAEKDQ 108
            |||. |..:.|...|.:.| .|..||:.|:.::.|:..|.                 |...|:|:
  Fly   878 SYDE-HDDEPGAGLGGNDEDDDDDEELDEEALAREMKMEQ-----------------NFVEEEDE 924

  Fly   109 NEPSNSDRYFCYDC-----HSI-------------------FENRN-------KAEEHICPRAES 142
            ::.:......|.:|     |.:                   .|.||       ||:.....:..|
  Fly   925 HDIAFRSHQSCRECSIAHDHKLCPLRNACGNVTDAVDLGEWIERRNLEALAKLKADAQRQAKRAS 989

  Fly   143 GGSSQQDGD------------------------------AKAP-------VRRKLASVSARTGPR 170
            |....:|.|                              |..|       |...:..|.|||..|
  Fly   990 GRQRHEDDDMEDMEDMDMDMDESSQLSELETKPLITFAEASVPAEFELHNVEPNVTGVFARTEVR 1054

  Fly   171 DASSVISCGICNTVFSSEKFLKFHMRIHENRAPKSIQDALPIGAHQQYSELDQFYCEICNK---- 231
             |.:.:...|...|.:.|        :.|....|.|.:....||       |:.|...|:.
  Fly  1055 -AFTKLGPLIGQPVQTGE--------VREGSDMKWIFEMCEAGA-------DKSYLLCCDNPNAS 1103

  Fly   232 ----------SFDE---TLLTVHKQMH-------------------------QQESSEIMCSICN 258
                      |::|   .|:::.:|.:                         ::.:.:..|..||
  Fly  1104 NWLRFVRPAPSYEERNVNLVSIDRQAYFVSCRDLRNGMELLYWSDDCNTMWRKKHTEKTNCGGCN 1168

  Fly   259 RKFENEVTYQMHQKIHEKPRDSESSRKLAQRTSLDKEKPGFPCQYCERVFTRPFEKVKH-ERVHT 322
            .|||:.:.|:.|..:...|..|.:.||             :.|:.|..........:|| ...|.
  Fly  1169 LKFEHPLYYRTHCSVFHDPSMSLTIRK-------------YHCKVCGEPVLGKDNIMKHAAEKHD 1220

  Fly   323 GEKPYACEVCGKTF-RVSYSLTLHLRTH------TNIRPYVCTVCNKRFKSHQVYSHHL-RIHSS 379
            |:..|.|:.|.|.| |::| |.:| ||:      ...|| ||..|.::|...|....|: |:||.
  Fly  1221 GKGAYQCQFCSKFFLRLNY-LEMH-RTYGCASNPNRSRP-VCDFCGRKFCQPQKLKAHIKRMHSD 1282

  Fly   380 E----RQFSCDACPKTFRTSVQLYAH-KNTHTK---PYRCAVCNRPFSSMYAVKNHMQTHKEISS 436
            .    |.|.|..|.|...:...|..| |..|::   ...|..|.:.|.:...:|.||.||
  Fly  1283 MAEVLRDFQCKLCSKLLGSRAALQRHSKEVHSRNSTVVSCPRCQKLFQNRSNLKIHMLTH----- 1342

  Fly   437 KGSVGSGTPNIKSAATSKSQAAGKFYCNTCGAEYARLFALRLHMKSAHGLVEEQENPATSTDAAH 501
                 ||....|.|...            |.|.:.....|:.|.|..|...:|| .|......|:
  Fly  1343 -----SGVRPFKCAEPE------------CNAAFTTKQCLQFHYKKVHNYTQEQ-MPKIERSVAY 1389

  Fly   502 VAET-----------DDSETAVLIAAAEADA 521
            ..:.           ..:.||...:||.|.|
  Fly  1390 TFDAYSGGMKVDFLGKQTATATPASAASAQA 1420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Opbp	NP_724479.1	C2H2 Zn finger	254..274	CDD:275368	8/19 (42%)
		C2H2 Zn finger	301..321	CDD:275368	4/20 (20%)
		zf-H2C2_2	316..336	CDD:290200	8/20 (40%)
		C2H2 Zn finger	329..349	CDD:275368	9/20 (45%)
		zf-H2C2_2	341..366	CDD:290200	10/30 (33%)
		C2H2 Zn finger	357..377	CDD:275368	6/20 (30%)
		C2H2 Zn finger	385..405	CDD:275368	6/20 (30%)
		C2H2 Zn finger	411..431	CDD:275368	6/19 (32%)
CG43347	NP_001138185.2	NR_DBD_like	1198..>1268	CDD:295381	23/72 (32%)
		C2H2 Zn finger	1198..1219	CDD:275368	4/20 (20%)
		C2H2 Zn finger	1227..1255	CDD:275368	10/29 (34%)
		C2H2 Zn finger	1259..1280	CDD:275368	6/20 (30%)
		C2H2 Zn finger	1292..1313	CDD:275368	6/20 (30%)
		C2H2 Zn finger	1322..1342	CDD:275368	6/19 (32%)
		zf-H2C2_2	1334..1361	CDD:290200	11/48 (23%)
		C2H2 Zn finger	1350..1373	CDD:275368	6/34 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100