Protein Alignment Ugt50B3 and Ugt1a6a

DIOPT Version :10

• Sequence 1: NP_724417.3
• Gene: Ugt50B3 / 246614
• FlyBaseID: FBgn0050438
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_659545.2
• Gene: Ugt1a6a / 94284
• MGIID: 2137698
• Length: 531
• Species: Mus musculus
• Alignment Length: 513
• Identity: 154/513 - (30%)
• Similarity: 257/513 - (50%)
• Gaps: 47/513 - (9%)

  Fly     7 LFLIIWSCGTLAADILMATQGGTKSHKIPFWELAKGLISRGHNI-------TFLSG--------- 55
            |||::|: ..|...:|:..|.|  ||.:...|:.:.|..|||:|       ..|.|
Mouse    16 LFLVLWA-SVLGDKLLVVPQDG--SHWLSMKEIVEHLSERGHDIMVLVPEVNLLLGESKYYRRKI 77

  Fly    56 FPADFNIEGLLEVTPAGLVEYIHNYTNWDLLGSRMAGEMPIKPWDG----LRYAFESCDAMLRDS 116
            |...:::|.|       ...:.....|..|.|:.:.|  |::.:..    :...|.:|.::|:||
Mouse    78 FSVTYSLEEL-------QTRFRTFGNNHFLPGASLMG--PLREYRNNMIVVDMFFSNCQSLLKDS 133

  Fly   117 ETKE-LTKKSFDLAILDGAFPECFLGLMYDFKIPFMYINTVGF---YTGSISTAGNPVSYAITPN 177
            .|.. |.:..||....|.|.| |.:.|.....:|.:|:.. ||   ....:..:.:||||  .|.
Mouse   134 ATLSFLRENKFDALFTDPAMP-CGVILAEYLNLPSVYLFR-GFPCSLEHMLGQSPSPVSY--VPR 194

  Fly   178 FYSRFTDTMNLYERAINTAMQIGQTLMHMYVMRRTHLVMREHLGTQIPHPYEMSRNVSFILQNGH 242
            ||::|:|.|...:|..|..:.|.:..::..:..:..::..:.|...:..| .:.:|..::|:...
Mouse   195 FYTKFSDHMTFPQRLANFIVNILENYLYYCLYSKYEIIASDLLKRDVSLP-SLHQNSLWLLRYDF 258

  Fly   243 AVLSYPRAFNPNVAEVACIHCRPARKLPRNLEEFIGASGASGFIYVSMGSSVKAANMPEALRHML 307
             |..|||...||:..:..|:|:...||.:..|.::.|||..|.:..|:||.|  :.:||.....:
Mouse   259 -VFEYPRPVMPNMIFLGGINCKKKGKLTQEFEAYVNASGEHGIVVFSLGSMV--SEIPEKKAMEI 320

  Fly   308 VKTFARLPYHVLWKYEGSSTDIKDITSNVKLSRWLPQQDILGHPKLRAFVTHGGLLSMFETVYHG 372
            .:...|:|..|||:|.|  |...::..|..|.:||||.|:|||||.|||:||.|...::|.:.:|
Mouse   321 AEALGRIPQTVLWRYTG--TRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNG 383

  Fly   373 VPVVTMPVFCDHDVNSAKAEVDGYAIKLDLQTLSANQLYKAIMKVIHNPRYRNSARHRQKLFLDQ 437
            ||:|.||:|.|...|:.:.|..|..:.|::..::|:.|..|:..||:|..|:.:......|..|:
Mouse   384 VPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDR 448

  Fly   438 RSTALDTAIYWTEYVLRHNGAYHLQTPSRNMTWWQYYLLDVVAVYL-ILLYVLILALR 494
            ....||.|::|.|||:||.||.||:..:.::||:||:.|||:...| |:|.|:.:..:
Mouse   449 PIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFK 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt50B3	NP_724417.3	Glycosyltransferase_GTB-type	43..480	CDD:471961	139/460 (30%)
Ugt1a6a	NP_659545.2	UDPGT	27..522	CDD:278624	149/501 (30%)