DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt50B3 and UGT74E2

DIOPT Version :9

Sequence 1:	NP_001260710.1	Gene:	Ugt50B3 / 246614	FlyBaseID:	FBgn0050438	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_172059.1	Gene:	UGT74E2 / 837075	AraportID:	AT1G05680	Length:	453	Species:	Arabidopsis thaliana

Alignment Length:	498	Identity:	94/498 - (18%)
Similarity:	166/498 - (33%)	Gaps:	181/498 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 KSHKIPFWELAKGLISRGHNITFLSGFPADFNIEGLLEVTPAGLVEYIH-NYTNWDLLGSRMAGE 93
            :.|..|..:..|.|.|:|..:|.:           |:...|:...:..| :.|.:.:......||
plant    15 QGHITPMSQFCKRLASKGLKLTLV-----------LVSDKPSPPYKTEHDSITVFPISNGFQEGE 68

  Fly    94 MPIKPWDGLRYAFESCDAMLR-DSETKELTKKSFDLAILDGAFPECFLGLMYDFKIPFM------ 151
            .|::..|         |.|.| ::..|....|..:...|.|..|.   .::||..:|::
plant    69 EPLQDLD---------DYMERVETSIKNTLPKLVEDMKLSGNPPR---AIVYDSTMPWLLDVAHS 121

  Fly   152 ------------YINTVGFY---TGSIS--------------------TAGNPVSY----AITPN 177
                        ::.|..:|   .||.|                    ||.:..|:    :..||
plant   122 YGLSGAVFFTQPWLVTAIYYHVFKGSFSVPSTKYGHSTLASFPSFPMLTANDLPSFLCESSSYPN 186

  Fly   178 FYSRFTDTMNLYERA----INT-----------------AMQIGQTLMHMYVMRRTHLVMREHLG 221
            ......|.::..:|.    .||                 .:.||.|:..||:.:|
plant   187 ILRIVVDQLSNIDRVDIVLCNTFDKLEEKLLKWVQSLWPVLNIGPTVPSMYLDKR---------- 241

  Fly   222 TQIPHPYEMSRNVSFILQNGHAVLSYPRAFNPNVAEVACIHCRPARKLPRNLEEFIGASGASGFI 286
                  ....:|..|.|            ||..|||  |:             |::.:...:..:
plant   242 ------LSEDKNYGFSL------------FNAKVAE--CM-------------EWLNSKEPNSVV 273

  Fly   287 YVSMGSSV---------KAANMPEALRHMLVKTFARLPYHVLWKYEGSSTD------IKDITSNV 336
            |:|.||.|         .||.:.::.|..            ||....:.|.      :::|....
plant   274 YLSFGSLVILKEDQMLELAAGLKQSGRFF------------LWVVRETETHKLPRNYVEEIGEKG 326

  Fly   337 KLSRWLPQQDILGHPKLRAFVTHGGLLSMFETVYHGVPVVTMPVFCDHDVNS------------A 389
            .:..|.||.|:|.|..:..|:||.|..|..|.:..|||::.||.:.|...|:            .
plant   327 LIVSWSPQLDVLAHKSIGCFLTHCGWNSTLEGLSLGVPMIGMPHWTDQPTNAKFMQDVWKVGVRV 391

  Fly   390 KAEVDGYAIKLDLQTLSANQLYKAIMKVIHNPRYRNSARHRQK 432
            |||.||:        :...::.:::.:|:...:.:...::.:|
plant   392 KAEGDGF--------VRREEIMRSVEEVMEGEKGKEIRKNAEK 426

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt50B3	NP_001260710.1	YjiC	28..434	CDD:224732	94/498 (19%)
Ugt50B3	NP_001260710.1	egt	<172..479	CDD:223071	60/313 (19%)
UGT74E2	NP_172059.1	Glycosyltransferase_GTB-type	6..450	CDD:415824	94/498 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000