Protein Alignment Ugt50B3 and ugt2a4

DIOPT Version :10

• Sequence 1: NP_724417.3
• Gene: Ugt50B3 / 246614
• FlyBaseID: FBgn0050438
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_001170804.2
• Gene: ugt2a4 / 791613
• ZFINID: ZDB-GENE-080721-23
• Length: 533
• Species: Danio rerio
• Alignment Length: 537
• Identity: 147/537 - (27%)
• Similarity: 250/537 - (46%)
• Gaps: 85/537 - (15%)

  Fly     6 ALFLIIWSCGTLAADI----LMATQGGTKSHKIPFWELAKGLISRGHNITFL--SGFPA------ 58
            ||.:.:..||   .|:    .:....|..||......:.:.|:.|.|::|.|  |..|.
Zfish     5 ALLVCLLLCG---VDVGWSGRVLVMPGEYSHWHNMRAIIEALVDRNHSVTVLVSSSSPTVPHTQK 66

  Fly    59 ---DFNIEGL-LEVTPAGLV--EYIH------------NYTNWDLLGS--RMAGEMPIKPWDGLR 103
               |:::..: ::...|.::  ::.|            .:..|.::.:  |:|.::
Zfish    67 ARFDYHVFKVNMDKEEAKVIWSDFTHLWMKETDSKLERGFLIWRVMSNFRRLAADV--------- 122

  Fly   104 YAFESCDAMLRDSETKELTKKS-FDLAILDGAFPECFLGLMYDFKIPFMYINTVGF-YT-----G 161
                 |.::|::.:..::..:| :|:...|...| |...:.....||.:....:.| ||     |
Zfish   123 -----CRSLLQNDDLLQMLGESHYDVLFSDPMMP-CSDLMAQTLNIPQVISLRLTFAYTFERMCG 181

  Fly   162 SISTAGNPVSYAITPNFYSRFTDTMNLYERAINTAMQIGQTLMHMYVMRRTHLVMREHLGTQI-P 225
            .:..   |.||..........||.|:..||..|..:.    .:|..|.|...::..:.|.|:| .
Zfish   182 QMPA---PPSYVPAVALTDHLTDRMSFMERVENMLLY----FIHTTVFRLNTMLTVDRLYTEIRG 239

  Fly   226 HPYEMSRNVSFILQNGHAVL---------SYPRAFNPNVAEVACIHCRPARKLPRNLEEFIGASG 281
            .|..|...:      |.|.:         .|||.|.||...|..:||:||:.|.:.:|||:.:||
Zfish   240 KPTTMCETM------GKADIWLIRTYWDFEYPRPFPPNFKFVGGLHCKPAKPLSKEMEEFVQSSG 298

  Fly   282 ASGFIYVSMGSSVKAANMPEALRHMLVKTFARLPYHVLWKYEGSSTDIKDITSNVKLSRWLPQQD 346
            ..|.:..|:||.:|  |:.....:.:.....::|..|:|:|.|.:.:  .:..|.|:..|:||.|
Zfish   299 DHGVVVFSLGSMIK--NLTSERANTIAAALGQIPQKVVWRYSGKTPE--TLAPNTKIYDWIPQND 359

  Fly   347 ILGHPKLRAFVTHGGLLSMFETVYHGVPVVTMPVFCDHDVNSAKAEVDGYAIKLDLQTLSANQLY 411
            :|||||.:||:||||...::|.:|||||:|.:|:|.|...|....:..|.|:.||:.||.:..|.
Zfish   360 LLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFADQPDNLLHMKTKGAAVVLDINTLESKDLV 424

  Fly   412 KAIMKVIHNPRYRNSARHRQKLFLDQRSTALDTAIYWTEYVLRHNGAYHLQTPSRNMTWWQYYLL 476
            .|:..|::||.|:.|.....::..||....||.|:||.|:|:|:.||.||:..:..::|:||:.|
Zfish   425 DALKTVLNNPSYKESIMRLSRIHHDQPMKPLDQAVYWIEFVMRNKGAKHLRVQAHELSWYQYHCL 489

  Fly   477 DVVAVYLILLYVLILAL 493
            | ||.:|:.:..||..|
Zfish   490 D-VAAFLLSIAALITFL 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt50B3	NP_724417.3	Glycosyltransferase_GTB-type	43..480	CDD:471961	133/481 (28%)
ugt2a4	NP_001170804.2	UDPGT	21..520	CDD:278624	142/518 (27%)