DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt50B3 and ugt8

DIOPT Version :9

Sequence 1:	NP_001260710.1	Gene:	Ugt50B3 / 246614	FlyBaseID:	FBgn0050438	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	XP_002934292.2	Gene:	ugt8 / 779534	XenbaseID:	XB-GENE-960667	Length:	537	Species:	Xenopus tropicalis

Alignment Length:	513	Identity:	155/513 - (30%)
Similarity:	259/513 - (50%)	Gaps:	56/513 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 ALFLIIW-SCG-TLAADILMATQGGTKSHKIPFWELAKGLISRGHNITFLSG------------- 55
            ::.|.:| :.| |.||.||:......:||...|..||..|..:||...||:.
Frog     6 SVILCLWIAVGVTKAAKILIVPPIMFESHLYIFKTLASALHEQGHQTVFLASEGRDIPQSSHYQV 70

  Fly    56 --FPADFNIEGLLEVTPAGLVEYIHNYTNWDLLGSRM----AGEM-PIKPWDGLRYAFESCDAML 113
              :|..||                 :.|:.:.|.|:|    :|.. .::.:|.|.:..::||.|:
Frog    71 QRYPGIFN-----------------SSTSDNFLQSKMMNIFSGRFTALELFDILDHYSKNCDIMV 118

  Fly   114 RDSE-TKELTKKSFDLAILDGAFPE--CFLGLMYDFKIPFMYINTVGFYTGSISTAGNPVSYAIT 175
            .:.: .:.|.::.|||.::|   |.  |...:.....:.:...:|..:|...:   |.|...|..
Frog   119 GNLDLMRRLKQEQFDLLLVD---PNEMCGFVIANILDVKYAVFSTGLWYPAEV---GAPAPLAYV 177

  Fly   176 PNFYSRFTDTMNLYERAINTAMQ-IGQTLMHMYVMRRTHLVMREHLGTQIPHPYEMSRNVSFILQ 239
            |.|.|..||.|||.:|..||.:. |.:..::..|:.:...:|:::........||:.:.....:.
Frog   178 PEFNSMLTDNMNLLDRIKNTFVYLISRIGVNFLVLPKYDRIMQKYNIFSTRSMYELVQGSCLWML 242

  Fly   240 NGHAVLSYPRAFNPNVAEVACIHCRPARKLPRNLEEFIGASGASGFIYVSMGSSVKAANMPEALR 304
            .....|.:||...|||..|..|..:|...||::|:.::.....:||:.||.|:.||  .:.|.:.
Frog   243 CTDIALEFPRPTLPNVVYVGGILTKPVSPLPQDLQTWVDNVDENGFVLVSFGAGVK--YLSEDIA 305

  Fly   305 HMLVKTFARLPYHVLWKYEGSSTDIKDITSNVKLSRWLPQQDILGHPKLRAFVTHGGLLSMFETV 369
            :.|....||||..|:|::.|  |..:::.:|.||..|:||.|:|||||::.|::||||..:||.:
Frog   306 NKLAGALARLPQKVIWRFSG--TKPRNLGNNTKLIEWIPQNDLLGHPKIKTFLSHGGLNGIFEAM 368

  Fly   370 YHGVPVVTMPVFCDHDVNSAKAEVDGYAIKLDLQTLSANQLYKAIMKVIHNPRYRNSARHRQKLF 434
            |||||||.:|:|.||.....:.:..|..|.|:.:.::.:.|:.::.:||||..|:..|.....:.
Frog   369 YHGVPVVGIPLFGDHYDTMTRVQAKGMGILLEWKKITEDTLFASLTEVIHNQSYQQQAVKLSTIH 433

  Fly   435 LDQRSTALDTAIYWTEYVLRHNGAYHLQTPSRNMTWWQYYLLDVVAVYLILLYVLILA 492
            .||....:..|:||..|:||||||.||:....|::::||:|||||   |:||:|:.:|
Frog   434 KDQPGHPVSRAVYWINYILRHNGADHLRAAIHNVSFYQYFLLDVV---LLLLFVVTIA 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt50B3	NP_001260710.1	YjiC	28..434	CDD:224732	120/429 (28%)
Ugt50B3	NP_001260710.1	egt	<172..479	CDD:223071	106/307 (35%)
ugt8	XP_002934292.2	Glycosyltransferase_GTB-type	21..472	CDD:415824	138/477 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H20715
Inparanoid	1	1.050	228	1.000	Inparanoid score	I3388
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm47564
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2881
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.080