Protein Alignment Ugt50B3 and ugt5a2

DIOPT Version :10

• Sequence 1: NP_724417.3
• Gene: Ugt50B3 / 246614
• FlyBaseID: FBgn0050438
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_001070191.3
• Gene: ugt5a2 / 767756
• ZFINID: ZDB-GENE-061103-373
• Length: 524
• Species: Danio rerio
• Alignment Length: 539
• Identity: 154/539 - (28%)
• Similarity: 249/539 - (46%)
• Gaps: 94/539 - (17%)

  Fly     5 IALFLIIWSC---GTLAADILMATQGGTKSHKIPFWELAKGLISRGHNITFLSG----------- 55
            :.|||::  |   .:.|..:|:....|  ||.:....|...|.||||:||.:.|
Zfish     7 LGLFLLL--CVLSRSYAGKLLVVPVEG--SHWVNMKVLIVELHSRGHSITVVRGSSSWYIEEQSP 67

  Fly    56 -----------FPADFN---IEGLLEVTPAGLVEYIHNYTNWDLLGSRMAGEMPIKPWDGLRYAF 106
                       |..||.   :..||::...|       .:.|:.:.  :|.||       :.:..
Zfish    68 LYTSITVDNGVFDDDFMETFLPHLLKIQRQG-------KSFWNEMA--LADEM-------IHFVT 116

  Fly   107 E----SCD--AMLRDSET--KELTKKSFDLAILDGAFPECFLGLMYDFKIPFMY-INTVGFYTGS 162
            |    ||:  |:|.::||  ..|...::|:.:.|.|:....| |.:...:|.:| :....:....
Zfish   117 ETHKQSCNMTAILFENETLMNSLKDAAYDVVLTDPAYGSGVL-LAHRLGLPLVYNVRWTVYGEAH 180

  Fly   163 ISTAGNPVSYAITPNFYSRFTDTMNLYERAINTAMQIGQTLMHMYVMRRTHLVMREHLGTQIPHP 227
            ...|.:|:||  .|....:.||.|...:|.:|               ..|::::|.........|
Zfish   181 FDIAPSPLSY--VPVSGLQLTDKMTFSQRVMN---------------MMTYIMIRYKYSKNFGSP 228

  Fly   228 YE------MSRNVSF--ILQNGHAVL-------SYPRAFNPNVAEVACIHCRPARKLPRNLEEFI 277
            |:      ...||:|  :||:....|       .:||...|||..:....|:||:.||.:||||:
Zfish   229 YQELTQKYFGPNVNFFSLLQDADLWLMRNDFTFEFPRPTMPNVVYMGGFQCKPAKPLPGDLEEFV 293

  Fly   278 GASGASGFIYVSMGSSVKAANMPEALRHMLVKTFARLPYHVLWKYEGSSTDIKDITSNVKLSRWL 342
            .:||..|.|.:|:|:..  ..:...|...:...||:||..|:|:|.|...  .::.:|..:..||
Zfish   294 QSSGEHGVIMMSLGTVF--GQLLSELNDEIAAAFAQLPQKVIWRYTGPRP--ANLGNNTLIVNWL 354

  Fly   343 PQQDILGHPKLRAFVTHGGLLSMFETVYHGVPVVTMPVFCDHDVNSAKAEVDGYAIKLDLQTLSA 407
            ||.|:|||||.:.||.|||...:.|.:|||||:|.:|:..|...|.::....|.|..::..||..
Zfish   355 PQNDLLGHPKTKLFVAHGGTNGLQEAIYHGVPIVGLPLAFDQPDNLSRMRAKGTAKIVEFATLDR 419

  Fly   408 NQLYKAIMKVIHNPRYRNSARHRQKLFLDQRSTALDTAIYWTEYVLRHNGAYHLQTPSRNMTWWQ 472
            ....:|:.:|:|||.||.:.:...||..||....||.||:|.|:|:|:.||.||:|.|..|:|.:
Zfish   420 AVFLEALKEVLHNPSYRENMQKLSKLHHDQPMKPLDRAIFWIEFVMRNKGAPHLRTQSFRMSWIE 484

  Fly   473 YYLLDVVAVYLILLYVLIL 491
            |..:||:...::::.|.:|
Zfish   485 YQSIDVILTLMLMVLVFVL 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt50B3	NP_724417.3	Glycosyltransferase_GTB-type	43..480	CDD:471961	142/485 (29%)
ugt5a2	NP_001070191.3	None