Protein Alignment Ugt50B3 and UGT2B7

DIOPT Version :9

• Sequence 1: NP_001260710.1
• Gene: Ugt50B3 / 246614
• FlyBaseID: FBgn0050438
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_001065.2
• Gene: UGT2B7 / 7364
• HGNCID: 12554
• Length: 529
• Species: Homo sapiens
• Alignment Length: 542
• Identity: 158/542 - (29%)
• Similarity: 259/542 - (47%)
• Gaps: 82/542 - (15%)

  Fly     2 LKKIALFLII-----WSCGTLAADILMATQGGTKSHKIPFWELAKGLISRGHNITFLSGFPA--- 58
            :|..::.|:|     :|.|.....::.|.:   .||.:....:...||.|||.:|.|:...:
Human     3 VKWTSVILLIQLSFCFSSGNCGKVLVWAAE---YSHWMNIKTILDELIQRGHEVTVLASSASILF 64

  Fly    59 DFNIEGLL--EVTPAGLVE-YIHNYTNWDLLGSRMAGEMPIKPWDGL-RYAF------------- 106
            |.|....|  |:.|..|.: .:.|:.           ...||.|..| :..|
Human    65 DPNNSSALKIEIYPTSLTKTELENFI-----------MQQIKRWSDLPKDTFWLYFSQVQEIMSI 118

  Fly   107 ------ESC-DAMLRDSETKELTKKSFDLAILDGAFPECFLGLMYDFKIPFMYINTVGF---YTG 161
                  :.| |.:......|::.:..||:...|..|| |...|...|.|||:|  ::.|   ||.
Human   119 FGDITRKFCKDVVSNKKFMKKVQESRFDVIFADAIFP-CSELLAELFNIPFVY--SLSFSPGYTF 180

  Fly   162 SISTAG--NPVSYAITPNFYSRFTDTMNLYERAINTAMQIGQTLMHMYV-----------MRRTH 213
            ...:.|  .|.||  .|...|..||.|...||..|.          :||           |::..
Human   181 EKHSGGFIFPPSY--VPVVMSELTDQMTFMERVKNM----------IYVLYFDFWFEIFDMKKWD 233

  Fly   214 LVMREHLGTQIPHPYEMSRNVSFILQNGHAVLSYPRAFNPNVAEVACIHCRPARKLPRNLEEFIG 278
            ....|.||........|.:...::::|... ..:|....|||..|..:||:||:.||:.:|:|:.
Human   234 QFYSEVLGRPTTLSETMGKADVWLIRNSWN-FQFPYPLLPNVDFVGGLHCKPAKPLPKEMEDFVQ 297

  Fly   279 ASGASGFIYVSMGSSVKAANMPEALRHMLVKTFARLPYHVLWKYEGSSTDIKDITSNVKLSRWLP 343
            :||.:|.:..|:||.|  :||.|...:::....|::|..|||:::|:..|...:  |.:|.:|:|
Human   298 SSGENGVVVFSLGSMV--SNMTEERANVIASALAQIPQKVLWRFDGNKPDTLGL--NTRLYKWIP 358

  Fly   344 QQDILGHPKLRAFVTHGGLLSMFETVYHGVPVVTMPVFCDHDVNSAKAEVDGYAIKLDLQTLSAN 408
            |.|:|||||.|||:||||...::|.:|||:|:|.:|:|.|...|.|..:..|.|:::|..|:|:.
Human   359 QNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFADQPDNIAHMKARGAAVRVDFNTMSST 423

  Fly   409 QLYKAIMKVIHNPRYRNSARHRQKLFLDQRSTALDTAIYWTEYVLRHNGAYHLQTPSRNMTWWQY 473
            .|..|:.:||::|.|:.:.....::..||....||.|::|.|:|:||.||.||:..:.::||:||
Human   424 DLLNALKRVINDPSYKENVMKLSRIQHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLTWFQY 488

  Fly   474 YLLDVVAVYLILLYVLILALRR 495
            :.|||:...|:.:..:|..:.:
Human   489 HSLDVIGFLLVCVATVIFIVTK 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt50B3	NP_001260710.1	YjiC	28..434	CDD:224732	129/448 (29%)
		egt	<172..479	CDD:223071	107/317 (34%)
UGT2B7	NP_001065.2	UDPGT	24..525	CDD:278624	153/521 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm40389
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.810