Protein Alignment Ugt50B3 and Ugt2a3

DIOPT Version :10

• Sequence 1: NP_724417.3
• Gene: Ugt50B3 / 246614
• FlyBaseID: FBgn0050438
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_082370.2
• Gene: Ugt2a3 / 72094
• MGIID: 1919344
• Length: 534
• Species: Mus musculus
• Alignment Length: 530
• Identity: 148/530 - (27%)
• Similarity: 250/530 - (47%)
• Gaps: 88/530 - (16%)

  Fly     9 LIIWSCGTLAADILMATQGGTKSHKIPFWELAKGLISRGHNITFL----------SGFPADF-NI 62
            :::|.|              ..||.:....:.:.|.:|||.:|.|          ...|..| ||
Mouse    26 VLVWPC--------------DMSHWLNLKTILEELGARGHEVTVLKYPSIIIDQSKRIPLHFENI 76

  Fly    63 EGLLEVTPAG---------LVEYIHNYTNWDLLGS------RMAGEMPIKPWDGLRYAFES-CDA 111
            ..|.|:..|.         .|..|.|.:.|:...:      ::.|:            ||| |.:
Mouse    77 PLLYEIETAENRLNEIANLAVNVIPNLSLWEAAKTLQDFFLQVTGD------------FESICRS 129

  Fly   112 MLRDSE-TKELTKKSFDLAILDGAFPECFLGLMYDFKIPFMYI--NTVGFY----TGSISTAGNP 169
            :|.:.: ..:|....:|:.::|...| |...:....:|||:|.  .::|:|    .|.:     |
Mouse   130 VLYNQKFMDKLRDAQYDVVVIDPVVP-CGELVAEVLQIPFVYTLRFSMGYYMEKHCGQL-----P 188

  Fly   170 VSYAITPNFYSRFTDTMNLYERAINTAMQIGQTLMHMYVMRRTHLVMREHLGTQIPHPYEMSRNV 234
            :..:..|...|..||.|...||..|...    :|:..|.:::......:...::     .:.|..
Mouse   189 IPLSYVPVVMSELTDNMTFTERVKNMMF----SLLFEYWLQQYDFAFWDQFYSE-----TLGRPT 244

  Fly   235 SFILQNGHAVL---------SYPRAFNPNVAEVACIHCRPARKLPRNLEEFIGASGASGFIYVSM 290
            :|....|.|.:         .:||.:.||...|..:||:||:.||:.:|||:.:||..|.:..|:
Mouse   245 TFCKTVGKADIWLIRTYWDVEFPRPYLPNFEFVGGLHCKPAKPLPKEMEEFVQSSGEHGVVVFSL 309

  Fly   291 GSSVKAANMPEALRHMLVKTFARLPYHVLWKYEGSSTDIKDITSNVKLSRWLPQQDILGHPKLRA 355
            ||.||  |:.|...:::....|::|..|||:|.|...  ..:.||.:|..|:||.|:|||||.:|
Mouse   310 GSMVK--NLTEEKANLIASVLAQIPQKVLWRYSGKKP--ATLGSNTRLFNWIPQNDLLGHPKTKA 370

  Fly   356 FVTHGGLLSMFETVYHGVPVVTMPVFCDHDVNSAKAEVDGYAIKLDLQTLSANQLYKAIMKVIHN 420
            |:||||...::|.:|||||:|.:|:..|...|.|..|..|.|:|:.:.|:::..|..|:..||:.
Mouse   371 FITHGGTNGIYEAIYHGVPMVGVPMLGDQPHNIAHMEAKGAALKVSISTMTSTDLLSAVRAVINE 435

  Fly   421 PRYRNSARHRQKLFLDQRSTALDTAIYWTEYVLRHNGAYHLQTPSRNMTWWQYYLLDVVAVYLIL 485
            |.|:.:|....::..||....||.|::|.|:|:||.||.||:..:.:::|:||:.|||:...|:.
Mouse   436 PSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLLC 500

  Fly   486 LYVLILALRR 495
            :..|...:.:
Mouse   501 VVTLTFIITK 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt50B3	NP_724417.3	Glycosyltransferase_GTB-type	43..480	CDD:471961	142/479 (30%)
Ugt2a3	NP_082370.2	UDPGT	25..526	CDD:278624	148/530 (28%)