DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt50B3 and RGD1559459

DIOPT Version :9

Sequence 1:	NP_001260710.1	Gene:	Ugt50B3 / 246614	FlyBaseID:	FBgn0050438	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	XP_003751392.1	Gene:	RGD1559459 / 501907	RGDID:	1559459	Length:	530	Species:	Rattus norvegicus

Alignment Length:	511	Identity:	145/511 - (28%)
Similarity:	246/511 - (48%)	Gaps:	79/511 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 SHKIPFWELAKGLISRGHNITFL------------------SGFPADFNIEGLLEVTPAGLVEYI 77
            ||.:....:...|:.:||.:..|                  ..||:.::|..:..:....:.|.|
  Rat    34 SHWLNLKIILSELVKKGHEVVVLKPSVSFSYEVDKTSAIEFESFPSSYSIADVEVIFMDCVNESI 98

  Fly    78 HNYTNWDLLGSRMAGEMPIKPWDG----LRYAFES----CDAMLRDSE-TKELTKK----SFDLA 129
            :              |:|.:.:.|    |:..||.    .:.:.||:. .|||..|    .||:.
  Rat    99 Y--------------ELPKQSFWGYFLMLQKLFERTSDYSERLCRDAAFNKELMTKLQNSGFDVI 149

  Fly   130 ILDGAFPECFLGLMYDFKIPFMYINTVGFYTGSI---STAGNPVSYAITPNFYSRFTDTMNLYER 191
            :.| .|..|...|....|||.:|  ::.|:.||.   .:.|.|:..:..|...|..:|.|...||
  Rat   150 LAD-PFTPCGDLLAEILKIPLVY--SLRFFPGSTYEKYSGGLPMPPSYVPIAMSELSDRMTFVER 211

  Fly   192 AINTAMQIGQTLMHM-YVM-----------RRTHLVMREHLGTQIPHPYEMSRNVSFILQNGHAV 244
                       :.|| ||:           ::.:.:..|.||........|::...::::. :..
  Rat   212 -----------VKHMIYVLCFDFWFQVFDEKKWNELYTEVLGRPTTLSETMAKADIWLIRT-YWD 264

  Fly   245 LSYPRAFNPNVAEVACIHCRPARKLPRNLEEFIGASGASGFIYVSMGSSVKAANMPEALRHMLVK 309
            |.:|....||...|..:|||||:.||:.:|:|:.:||..|.:..|:||.|  .::.|...:::..
  Rat   265 LEFPHPVLPNFDFVGGLHCRPAKPLPKEIEDFVQSSGEHGVVVFSLGSMV--GSLTEERANVIAA 327

  Fly   310 TFARLPYHVLWKYEGSSTDIKDITSNVKLSRWLPQQDILGHPKLRAFVTHGGLLSMFETVYHGVP 374
            ..|::|..|||::||...:  .:.||.:|.:|:||.|:|||||.|||:||||...::|.:|||:|
  Rat   328 GLAQIPQKVLWRFEGKKPE--TLGSNTRLYKWIPQNDLLGHPKTRAFITHGGTNGIYEAIYHGIP 390

  Fly   375 VVTMPVFCDHDVNSAKAEVDGYAIKLDLQTLSANQLYKAIMKVIHNPRYRNSARHRQKLFLDQRS 439
            ||.:|:|.|...|....:..|.|::||..|:|:..|..|:..|.::|.|:.:|....::..||..
  Rat   391 VVGIPLFGDQKDNIVHLKTKGAAVRLDFLTMSSTDLLTALRTVTNDPSYKENAMRLSRIHHDQPV 455

  Fly   440 TALDTAIYWTEYVLRHNGAYHLQTPSRNMTWWQYYLLDVVAVYLILLYVLILALRR 495
            ..||.|::|.|:|:||.||.||:....:::|.||:.|||:...|..:..::..|::
  Rat   456 KPLDRAVFWIEFVMRHKGAKHLRVAGHDLSWVQYHSLDVIGFLLACVVTVMFILKK 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt50B3	NP_001260710.1	YjiC	28..434	CDD:224732	123/448 (27%)
Ugt50B3	NP_001260710.1	egt	<172..479	CDD:223071	104/318 (33%)
RGD1559459	XP_003751392.1	UDPGT	24..527	CDD:278624	145/511 (28%)
RGD1559459	XP_003751392.1	egt	<270..508	CDD:223071	90/241 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm44525
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.810