DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt50B3 and ugt3a2

DIOPT Version :9

Sequence 1:	NP_001260710.1	Gene:	Ugt50B3 / 246614	FlyBaseID:	FBgn0050438	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_001005027.3	Gene:	ugt3a2 / 448540	XenbaseID:	XB-GENE-5824772	Length:	523	Species:	Xenopus tropicalis

Alignment Length:	525	Identity:	149/525 - (28%)
Similarity:	237/525 - (45%)	Gaps:	47/525 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KKIALFLIIWSCGTL-AADIL-MATQGGTKSHKIPFWELAKGLISRGHNIT--------FLSGF- 56
            |.:.|.|::.....| .|.|| :...||  ||.:...::::.|.:.||.:|        ||.|:
Frog     6 KSLILCLLVQHFVLLQGAKILTVCLAGG--SHYLWMDKISRILHNNGHEVTMFRQTADNFLPGYR 68

  Fly    57 ----PADFNIEGLLEVTPAGLVEYIHNYTNWDLLGSRMAGEMPIKPWDGLRYAFESCDAMLRDSE 117
                |....|..:.|.:....:.:.........:|..     .:...|.:.:....|..:...:.
Frog    69 TPDSPYRVVIWSMDETSQKEFIAFFKENMKLSFMGGH-----DLSLLDLMAHLSSQCKMIFNQTS 128

  Fly   118 TKELTK-KSFDLAILDGAFPECFLGLMYDFKIPFMYINTVGFYTGSISTAGNPVSYAITPNFYSR 181
            ...|.| :.:|:|::| :|..|...:.....|||  |.|..|...:...:|.|...:..|.|.::
Frog   129 IINLLKEEKYDIAVID-SFNPCSFLVSEKLGIPF--IATHPFALKNAWHSGIPNQLSYVPVFQTQ 190

  Fly   182 FTDTMNLYERAINTAMQIGQTLMHMYVMRRTHLVMREHL--GTQIPHPYEMSRNVSFILQNGHAV 244
            .||.|:.:||..|..|.||..:....:......|:.||.  |:: |...|:.:..:..:.|....
Frog   191 LTDHMDFFERVKNVLMYIGSRVEESKIHSLFDDVIEEHFPAGSR-PTFVELYKKTALWMYNTDFT 254

  Fly   245 LSYPRAFNPNVAEVACIHCRPARKLPRNLEEFIGASGASGFIYVSMGSSVKAANMPEALRHMLVK 309
            ..:...|.|||..:..:..:||..:.:.||:||..||..|||.|:.||.|.::...|.::.| ..
Frog   255 FEFSHPFFPNVLYIGGLLAKPANPVSQELEDFISQSGEHGFIIVAFGSMVSSSPFTEFVKEM-ND 318

  Fly   310 TFARLPYHVLWKYEGSSTDIK-DITSNVKLSRWLPQQDILGHPKLRAFVTHGGLLSMFETVYHGV 373
            .||::|..|:|:|..|....: .:..|||:..|:.|.|:|||||.|..|||||:.|:.|.:||||
Frog   319 GFAKIPQKVIWRYRISEWPKEVQLAPNVKIMDWISQNDLLGHPKARLLVTHGGINSVQEAIYHGV 383

  Fly   374 PVVTMPVFCDHDVNSAKAEVDGYAIKLDLQTLSANQLYKAIMKVIHNPRYRNSARHRQKLFLDQR 438
            |:|.:|:|.|...|:.:.:.......:....|.|.....||..||.:..|:|||.|   ..|.||
Frog   384 PMVAIPLFGDQFDNAVRIKAKHLGTFILPGQLKAEDFANAIRHVIEDESYKNSAMH---FSLIQR 445

  Fly   439 STAL---DTAIYWTEYVLRHNGAYHLQTPSRNMTWWQYYLLDVV---------AVYLILLYVLIL 491
            |...   ...:.|.|:::...||.||...|.....:|.|||||:         |.|| .:.||.|
Frog   446 SQPFPKEQQIVRWVEHIVTVGGANHLIPYSYQQPLYQQYLLDVILFVCVCFIGACYL-TVKVLRL 509

  Fly   492 ALRRI 496
            .::|:
Frog   510 FIQRL 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt50B3	NP_001260710.1	YjiC	28..434	CDD:224732	117/422 (28%)
Ugt50B3	NP_001260710.1	egt	<172..479	CDD:223071	102/312 (33%)
ugt3a2	NP_001005027.3	UDPGT	23..519	CDD:278624	145/508 (29%)
ugt3a2	NP_001005027.3	egt	<235..435	CDD:223071	67/200 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000