DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt50B3 and Ugt36F1

DIOPT Version :9

Sequence 1:	NP_001260710.1	Gene:	Ugt50B3 / 246614	FlyBaseID:	FBgn0050438	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster

Alignment Length:	501	Identity:	144/501 - (28%)
Similarity:	246/501 - (49%)	Gaps:	39/501 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 AADILMATQGGTKSHKIPFWELAKGLISRGHNITFLSGFP--------ADFNIEGLLEVTPAGLV 74
            ||.||...|...|||...|..:...|..|||||:..|.||        .|:..:|:..:|  .:|
  Fly    20 AAHILGLFQHPGKSHFDFFRPMFLALAERGHNISMYSYFPLEKPVANYTDYVFQGMPLLT--DIV 82

  Fly    75 EYIHNYTNWDLLGSRMAGEMPIK--------PWDGLRYAFESCDAMLRDSETKELTKK--SFDLA 129
            :..:..:.|..||      :|.|        .| |||    ||...|......:|.|.  .:|:.
  Fly    83 DLSNFESEWKPLG------LPFKVPTYFMLHDW-GLR----SCKVALNSPLITQLLKSPIRYDVI 136

  Fly   130 ILDGAFPECFLGLMYDFKIPFMYINTVGFYTGSISTAGNPVSYAITPNFYSRFTDTMNLYERAIN 194
            :|:....:|...:.:....|.:.:::...........|:|....|.|..:..:||.|:|.:|..|
  Fly   137 LLEHFSNDCMAAVAHLLNAPVIALSSCAIMPWHYKRMGSPFINPIMPMNFLPYTDEMSLIDRLNN 201

  Fly   195 -TAMQIGQTLMHMYVMRRTHLVMREHLGTQIPHPYEMSRNVSFILQNGHAVLSYPRAFNPNVAEV 258
             .......||.:|.....|..::.|..|..:|...|:.:|.|.:|.|.|..|:.||.:.|||.||
  Fly   202 FFHFHTVNTLYNMITQPATDALIAERFGPGLPPINEIVKNTSLMLINQHYALTGPRPYAPNVIEV 266

  Fly   259 ACIHCRPARKLPRNLEEFIGASGASGFIYVSMGSSVKAANMPEALRHMLVKTFARLP---YHVLW 320
            ..:...|.:.||::|.:.:..| .:|.||:|.||.|.:..:|...|..|.::.::|.   :.:.|
  Fly   267 GGLQVGPIKPLPQHLLDLLDRS-PNGVIYISWGSMVNSNTLPSGKRSALFQSISQLKEYNFVMRW 330

  Fly   321 KYEGSSTDIKDITSNVKLSRWLPQQDILGHPKLRAFVTHGGLLSMFETVYHGVPVVTMPVFCDHD 385
            |...|..|.:  .||:....||||:|:|.|||:|||::|||||...|.::.|||::..|.:.|..
  Fly   331 KSLESLEDKQ--PSNLYTFDWLPQRDLLCHPKIRAFISHGGLLGTTEAIHCGVPMLVTPFYGDQF 393

  Fly   386 VNSAKAEVDGYAIKLDLQTLSANQLYKAIMKVIHNPRYRNSARHRQKLFLDQRSTALDTAIYWTE 450
            :||...:..|:.:.:|.:...:|.:.:. :::|.:.::....|...:.|..:....:..|.:|.|
  Fly   394 LNSGAVKQRGFGVIVDFRDFDSNHITRG-LRIILDKKFAERVRRSSEAFRQRPIPPIKLATWWIE 457

  Fly   451 YVLRHNGAYHLQTPSRNMTWWQYYLLDVVAVYLILLYVLILALRRI 496
            :|:::.||.|:|:.:|::.|..|..:||:..:|.:|::||:|||::
  Fly   458 HVIKYGGAPHIQSEARHINWIVYNSIDVLLFWLGILFLLIVALRKL 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt50B3	NP_001260710.1	YjiC	28..434	CDD:224732	118/427 (28%)
Ugt50B3	NP_001260710.1	egt	<172..479	CDD:223071	94/310 (30%)
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	137/483 (28%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	120/439 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	172	1.000	Inparanoid score	I2735
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	8	7.960