DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt50B3 and F10D2.8

DIOPT Version :9

Sequence 1:	NP_001260710.1	Gene:	Ugt50B3 / 246614	FlyBaseID:	FBgn0050438	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_001309630.1	Gene:	F10D2.8 / 266913	WormBaseID:	WBGene00017334	Length:	494	Species:	Caenorhabditis elegans

Alignment Length:	521	Identity:	119/521 - (22%)
Similarity:	213/521 - (40%)	Gaps:	77/521 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 FLIIWSC--GTLAADILMATQGGTKSHKIPFWELAKGLISRGHNITFLSGFPADFNIEGLLEVTP 70
            ||:|.|.  .|.:.:.|:.......||...|..:|..|...|||:||.               ||
Worm     4 FLVILSLIYSTYSYNFLVFCPLFGHSHTKFFATIADALTDAGHNVTFF---------------TP 53

  Fly    71 AGLVEYIHNYTNWDLLGSRMAGEMPIKPWDGLRYA--FESCDAMLRDSETKELTKKS--FDLAIL 131
            . :||...|.:...|....:..:.|.|.   :.|.  .||.|.      ::..|:.|  :::...
Worm    54 T-IVEKYRNVSYTKLTKDVVHMDAPKKL---MEYGEQMESADF------SRFWTEDSSFYNVGAA 108

  Fly   132 DGAFPECFLGLMYDFKIPFMYINTVGFYTGSIS---------TAGNPVSYAITPNFYSRFTDTMN 187
            |  ...|.:.|...||....|:| :..:..|:|         ..|.||..::..:..|.|.|.::
Worm   109 D--LYRCSIRLNGLFKSLMDYLN-IKTFIPSLSLTHDVYLSKAIGEPVMPSVVSDVCSPFGDKLS 170

  Fly   188 LYERAINTAMQIGQTLMHMYVMRRTHLVMREHLGTQIPHPY------EMSRNVSFILQNGHAVLS 246
            |.|||.|.           :.:....:|:...:...:..||      .:....||:..|.:..|.
Worm   171 LLERAFNA-----------FAVPYIDIVLGYPVHNTLSAPYTEIDIRTIEPEASFLFLNSNPFLD 224

  Fly   247 YPRAFNPNVAEVACI----HCRPARKLPRNLEEFIGASGASGFIYVSMGSSVKAANMPEALRHML 307
            :||.......|:..|    :...:::|.....:.:.....:  :.||.||...:.:||...:.::
Worm   225 FPRPTLTKTVEIGGITVDLNQLKSQQLDSKWSDILNLREKT--MLVSFGSVFFSKDMPLENKKVI 287

  Fly   308 VKT---FARLPYHVLWKYEGSSTDIKDIT---SNVKLSRWLPQQDILGHPKLRAFVTHGGLLSMF 366
            ..:   |..:.:  :|||||:  ||:|..   .|:...:|:||..:|.:.:|.||.||.||.|:.
Worm   288 ANSMTEFKNVTF--IWKYEGN--DIEDFARGIQNIHFVKWVPQTALLANRRLSAFFTHAGLGSIN 348

  Fly   367 ETVYHGVPVVTMPVFCDHDVNSAKAEVDGYAIKLDLQTL-SANQLYKAIMKVIHNPRYRNSARHR 430
            |..|.|.|.:..|:|.|...|:........:|:|....| ::.::.:|...::.:..|..:|:..
Worm   349 EVSYLGKPSILCPLFADQMRNAKMLVRHNGSIELSKYDLGNSKKIIEAFQAILFDSSYAENAQKL 413

  Fly   431 QKLFLDQRSTALDTAIYWTEYVLRHNGAYHLQTPSRNMTWWQYYLLDVVAVYLILLYVLILALRR 495
            .:...:|........:...|:..|......|...||.|::.:|:||||..:.:::|..::..|.|
Worm   414 AEQLENQPIKPEKMMVKHAEFAARFGRLPSLDPYSRKMSFVEYFLLDVATICVLVLACVVFVLTR 478

  Fly   496 I 496
            :
Worm   479 V 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt50B3	NP_001260710.1	YjiC	28..434	CDD:224732	98/435 (23%)
Ugt50B3	NP_001260710.1	egt	<172..479	CDD:223071	73/323 (23%)
F10D2.8	NP_001309630.1	UDPGT	29..492	CDD:278624	113/496 (23%)
F10D2.8	NP_001309630.1	Glycosyltransferase_GTB_type	<215..461	CDD:299143	59/251 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810