Protein Alignment Ugt50B3 and ugt-2

DIOPT Version :10

• Sequence 1: NP_724417.3
• Gene: Ugt50B3 / 246614
• FlyBaseID: FBgn0050438
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_505672.2
• Gene: ugt-2 / 179450
• WormBaseID: WBGene00007073
• Length: 531
• Species: Caenorhabditis elegans
• Alignment Length: 559
• Identity: 140/559 - (25%)
• Similarity: 231/559 - (41%)
• Gaps: 100/559 - (17%)

  Fly     7 LFLIIW-----SCGTLAADILMATQGGTKSHKIPFWELAKGLISRGHNITFLSGFPADF------ 60
            |||:::     .|..||.:.|:.......||.....::|..|.:..||:|.|..:..:.
 Worm     3 LFLLVFLFFALYCNVLAYNYLVVAPVFGYSHMKFMNKVADTLANGKHNVTLLQTYIYEHWGKIRI 67

  Fly    61 ----NIEGLLEVTPAGLVEYIHNYTN--------------WD--LLGSRMAGEM--------PIK 97
                |||         :::| ||..|              ||  ::.:.:.|.|        ..|
 Worm    68 VKNKNIE---------IIDY-HNSENVPSNEQSASAFKFFWDNEIVNNPITGAMAPMFILYNEFK 122

  Fly    98 PWDGLRYAFESCDAMLRDSETKE-LTKKSFDLAILDGAFPECFLGLMYDFKIPFM-YINTVGFYT 160
            |         .||.:|.|.|..: :....||..:.: :|..|.|.|....|:..: ..:|:....
 Worm   123 P---------MCDRILTDKELHQWILSNKFDGYVAE-SFDFCSLYLGDHLKLNLLPMFSTIKNVP 177

  Fly   161 GSISTAGNPVSYAITPNFYSRFTDTMNLYERAIN-TAMQIGQTLMHMYVMRRTHLVMREH----- 219
            || ...|.|......|:.|:.|.....:::|..: ||.    |..| |..  ::|..|::
 Worm   178 GS-HAIGEPSLLNYAPSLYTNFGSDQTVWDRIQDITAF----TSFH-YAF--SNLFERQYRQAYD 234

  Fly   220 -LGTQIPHPYEMSRNVSFILQNGHAVLSYPRAFNPNVAEVACIHCRPARKLPRNLEEFIGASG-A 282
             |...:....|:.:..::...|.:..:.:.........|:......|...|..| |||..... .
 Worm   235 LLNGDVRTWREILQTATYFFYNNNPYIGFAMPTLEKSVEIGGFTIDPPHDLSLN-EEFDKLLDLR 298

  Fly   283 SGFIYVSMGSSVKAANMPEALRHMLVKTFARLP-YHVLWKYEGSSTDI-KDITSNVKLSRWLPQQ 345
            ...:.:|.|:.|::|:|||..:..|:|.||:|| ...:||||....:. |.::.||.|.:|:||.
 Worm   299 KSTVLISFGTVVQSADMPENFKSGLIKMFAKLPDTTFIWKYEVEDAEFSKTLSENVFLKKWIPQP 363

  Fly   346 DILGHPKLRAFVTHGGLLSMFETVYHGVPVVTMPVFCDHDVNSAKAEVDGYAIKLDLQTL-SANQ 409
            .:|..|:|..|:|||||.|..|..|.|.|.:.:|:|.|..:|:......|.||..|...| :..:
 Worm   364 ALLADPRLNLFITHGGLGSTLEVAYAGKPSLMIPIFGDQMLNAKMLSRHGGAISYDKYELENYEK 428

  Fly   410 LYKAIMKVIHNPRYRNSA------RHRQKLFLDQRSTALDTAIYWTEYVLRHNGAYHLQTPSRNM 468
            |.:.:.:.|.|..|...|      .|.|.  :|.:...|..|    |:..:....:.|:..|.:.
 Worm   429 LTETVKEAISNKEYNKKALLLAEILHNQP--IDPKQNLLKHA----EFTAKFGRVHALEPYSVHY 487

  Fly   469 TWWQYYLLDVVAV----YLILLYVLILALRRIDFPYEKV 503
            .:.:||:||..|:    :|.:||||.|.::   |.|.|:
 Worm   488 NFIKYYMLDAYAIIIIFFLSILYVLNLIIK---FVYRKI 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt50B3	NP_724417.3	Glycosyltransferase_GTB-type	43..480	CDD:471961	120/489 (25%)
ugt-2	NP_505672.2	GT1_Gtf-like	24..453	CDD:340817	111/457 (24%)