Protein Alignment Ugt50B3 and UGT3A1

DIOPT Version :9

• Sequence 1: NP_001260710.1
• Gene: Ugt50B3 / 246614
• FlyBaseID: FBgn0050438
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_689617.3
• Gene: UGT3A1 / 133688
• HGNCID: 26625
• Length: 523
• Species: Homo sapiens
• Alignment Length: 531
• Identity: 151/531 - (28%)
• Similarity: 234/531 - (44%)
• Gaps: 79/531 - (14%)

  Fly     3 KKIALFLIIWSCGTL---AADIL-MATQGGTKSHKIPFWELAKGLISRGHNITFL--SGFPADFN 61
            :::.|.:.....|.|   ||.|| ::|.||  ||.:....:::.|...|||:|.|  ||   .|.
Human     4 QRVLLLVAFLLSGVLLSEAAKILTISTLGG--SHYLLLDRVSQILQEHGHNVTMLHQSG---KFL 63

  Fly    62 IEGLLEVTPAGLV--------------EYIHNYTNWDLLGSRMAGEMPIKPWDGLRYAF-ESCDA 111
            |..:.|...:..|              ::..:|....|.| |...|..:|    |...| ..|..
Human    64 IPDIKEEEKSYQVIRWFSPEDHQKRIKKHFDSYIETALDG-RKESEALVK----LMEIFGTQCSY 123

  Fly   112 ML-RDSETKELTKKSFDLAILDGAFPECFLGLMYDFKIPFMYINTVGFYTGSISTA-GNPVSYAI 174
            :| |......|..:::||..:: ||..|...:......||:.|....|  ||:... .:|:||
Human   124 LLSRKDIMDSLKNENYDLVFVE-AFDFCSFLIAEKLVKPFVAILPTTF--GSLDFGLPSPLSY-- 183

  Fly   175 TPNFYSRFTDTMNLYERAINTAMQIGQTLMHMYVMRRTHLVMREHLGTQI-PHPYEMSRNV-SFI 237
            .|.|.|..||.|:.:.|..|..|        .:...|:...|:......| .|..|.||.| |.:
Human   184 VPVFPSLLTDHMDFWGRVKNFLM--------FFSFSRSQWDMQSTFDNTIKEHFPEGSRPVLSHL 240

  Fly   238 L-------QNGHAVLSYPRAFNPNVAEVACIHCRPARKLPRNLEEFIGASGASGFIYVSMGSSVK 295
            |       .|......:.|...||...:..:..:|.:.:|::|:.||...|.:||:.|:.||.:.
Human   241 LLKAELWFVNSDFAFDFARPLLPNTVYIGGLMEKPIKPVPQDLDNFIANFGDAGFVLVAFGSMLN 305

  Fly   296 AANMPEALRHMLVKTFARLPYHVLWKYEGS--STDIKDITSNVKLSRWLPQQDILGHPKLRAFVT 358
            .....|.|:.| ...||.||..|:|..:.|  ..|: .:.:|||:..||||.|:|.||.:|.|||
Human   306 THQSQEVLKKM-HNAFAHLPQGVIWTCQSSHWPRDV-HLATNVKIVDWLPQSDLLAHPSIRLFVT 368

  Fly   359 HGGLLSMFETVYHGVPVVTMPVFCDHDVNSAKAEVDGYAIKLDLQTLSANQLYKAIMKVIHNPRY 423
            |||..|:.|.:.||||:|.:||..|...|..:.....|.:.:.|..::|:.|...:.:||.:.||
Human   369 HGGQNSVMEAIRHGVPMVGLPVNGDQHGNMVRVVAKNYGVSIRLNQVTADTLTLTMKQVIEDKRY 433

  Fly   424 RNSA------RHRQKLFLDQRSTALDTAIYWTEYVLRHNGAYHLQTPSRNMTWWQYYLLDVVAVY 482
            :::.      .|.|.|...||      .:.|.:::|:..||.||:..:....|.:.||:||
Human   434 KSAVVAASVILHSQPLSPAQR------LVGWIDHILQTGGATHLKPYAFQQPWHEQYLIDV---- 488

  Fly   483 LILLYVLILAL 493
                :|.:|.|
Human   489 ----FVFLLGL 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt50B3	NP_001260710.1	YjiC	28..434	CDD:224732	125/441 (28%)
		egt	<172..479	CDD:223071	98/323 (30%)
UGT3A1	NP_689617.3	UDPGT	23..523	CDD:330975	147/512 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45374
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.820