Protein Alignment Ugt50B3 and Ugt2b37

DIOPT Version :10

• Sequence 1: NP_724417.3
• Gene: Ugt50B3 / 246614
• FlyBaseID: FBgn0050438
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_444445.2
• Gene: Ugt2b37 / 112417
• MGIID: 2148239
• Length: 530
• Species: Mus musculus
• Alignment Length: 512
• Identity: 149/512 - (29%)
• Similarity: 246/512 - (48%)
• Gaps: 61/512 - (11%)

  Fly    43 LISRGHNITFLSGFPADFNI------EGL-LEVTPAGLVE--------YIHNYTNWDLLGSRMAG 92
            |:.|||.:|.|.  |:.:.:      .|| .|..|..:.:        .:.|...::|.......
Mouse    46 LVQRGHEVTVLR--PSAYYVLDPKKSPGLKFETFPTSVTKDDLENFFIQLLNVWTYELSRDTCLS 108

  Fly    93 EMPI--KPWDGLR-YAFESCDAML--RDSETKELTKKSFDLAILDGAFPECFLG-----LMYDFK 147
            ..|:  ..:|.|. |....|..::  |...|| |.:..||:.:.|   |..|.|     |::
Mouse   109 YSPLMQNMFDELSGYYLSLCKDVVSNRQLMTK-LQESKFDVLLSD---PVAFGGELIAELLH--- 166

  Fly   148 IPFMYINTVGFYTG--SISTAGN---PVSYAITPNFYSRFTDTMNLYERAIN-TAMQIGQTLMHM 206
            |||:|  ::.|..|  ...::|.   |.||  .|...|.....|...||..| ..|........|
Mouse   167 IPFLY--SLRFTAGYRIEKSSGRFLLPPSY--VPVILSGLGGQMTFIERVKNMICMLYFDFWFQM 227

  Fly   207 YVMRRTHLVMREHLGTQIPHPYEMSRNVSFILQNGHAVLSYPRAFNPNVAEVACIHCRPARKLPR 271
            ...::......|:||........|.:...:::::... |.:|....|||..|..:||:||:.||:
Mouse   228 PNDKKWDSFYTEYLGRPTTLAETMGQAEMWLIRSNWD-LEFPHPTLPNVDYVGGLHCKPAKPLPK 291

  Fly   272 NLEEFIGASGASGFIYVSMGSSVKAANMPEALRHMLVKTFARLPYHVLWKYEGSSTDIKDITSNV 336
            ::||::.:||..|.:..|:||.|  :|:.|...:.:....|::|..||||::|.:.  ..:..|.
Mouse   292 DMEEYVQSSGDHGVVVFSLGSMV--SNITEEKVNAIAWALAQIPQKVLWKFDGKTP--ATLGHNT 352

  Fly   337 KLSRWLPQQDILGHPKLRAFVTHGGLLSMFETVYHGVPVVTMPVFCDHDVNSAKAEVDGYAIKLD 401
            ::.:||||.|:|||||.:||:||||..|::|.:|||:|::.:|:|.:...|.|.....|.|:.|:
Mouse   353 RVYKWLPQNDLLGHPKTKAFITHGGANSVYEAIYHGIPMIGIPLFGEQHDNIAHMVAKGAAVTLN 417

  Fly   402 LQTLSANQLYKAIMKVIHNPRYRNSARHRQKLFLDQRSTALDTAIYWTEYVLRHNGAYHLQTPSR 466
            ::|:|.:.:..|:.:||.||.|:.:|.....:..||....||.|::|.|:|:||..|.||:....
Mouse   418 IRTMSRSDVLNALEEVIENPFYKKNAMWLSTIHHDQPMKPLDRAVFWVEFVMRHKNAKHLRPLGH 482

  Fly   467 NMTWWQYYLLDVVAVYL-ILLYVLILALRRIDFPYEKVRSLYSLMAPFITIAKTKSK 522
            |:||:||:.|||:...| .:...::|.::.:.|.|.           |....|.|.|
Mouse   483 NLTWYQYHSLDVIGFLLACVAATVVLTVKCLLFIYR-----------FFVTKKKKMK 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt50B3	NP_724417.3	Glycosyltransferase_GTB-type	43..480	CDD:471961	141/467 (30%)
Ugt2b37	NP_444445.2	UDPGT	24..527	CDD:278624	147/509 (29%)