DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt50B3 and ugt5f1

DIOPT Version :9

Sequence 1:	NP_001260710.1	Gene:	Ugt50B3 / 246614	FlyBaseID:	FBgn0050438	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	XP_017207383.1	Gene:	ugt5f1 / 100415800	ZFINID:	ZDB-GENE-100406-6	Length:	556	Species:	Danio rerio

Alignment Length:	519	Identity:	152/519 - (29%)
Similarity:	248/519 - (47%)	Gaps:	70/519 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 CGTLAADILMATQGGTKSHKIPFWELAKGLISRGHNITFLSGFPA-----------DFNIEGLLE 67
            ||    .||:....|  ||.:....|.:.|..|||.|:.:....:           ..|:..||
Zfish    51 CG----KILVFPHEG--SHWLNLNTLIEELHHRGHQISVIRALDSWYIPETSPHYDSINVPFLL- 108

  Fly    68 VTPAGLVEYIHNY----------TNW-----DLLGSRMAGEMPIKPWDGLRYAFESCDAMLRDSE 117
               .|..::.|::          ..|     |:.......||..|..:.:.:..|...|::
Zfish   109 ---GGDDQFYHSFIFRQLQIRREQRWTRFKLDMELKEKFSEMHRKICEMVIHIVEKEPAIM---- 166

  Fly   118 TKELTKKSFDLAILD-----GAFPECFLGLMYDFKIPFMYINTVGFYTGSISTAGNPVSYAITPN 177
             |::.:.:||:.:.|     |.....:|.|...|.:.:.......|     :.|.:|.||...|
Zfish   167 -KQIKEANFDIMLTDPANGGGVVLAHYLHLPLVFNVQWTVHGEAHF-----AIAPSPPSYVPFP- 224

  Fly   178 FYSRFTDTMNLYERAINTAMQIGQTLMHMYVMRRT-----HLVMREHLGTQIPHPYEMSRNVSFI 237
             .|:.||:|:..:|..|...    :.:.:::.|||     ..:.....|..:.: :|:.:.....
Zfish   225 -LSQLTDSMSFPQRIYNVLF----SAVRLFLYRRTVGPHYSALCNRLFGPGLDY-FELFQAADIW 283

  Fly   238 LQNGHAVLSYPRAFNPNVAEVACIHCRPARKLPRNLEEFIGASGASGFIYVSMGSSVKAANMPEA 302
            |.....|..:||...|||..:...||.||:.||::||:|:.:||..|.|.:|:|:.|  |.:|..
Zfish   284 LMRADFVFDFPRPTMPNVIYIGGFHCSPAKALPKDLEDFLQSSGEHGVIVMSLGTLV--AQLPMD 346

  Fly   303 LRHMLVKTFARLPYHVLWKYEGSSTDIKDITSNVKLSRWLPQQDILGHPKLRAFVTHGGLLSMFE 367
            :...:|..||.||..|:|:|.|...  .::.:|..|..||||.|:|||||.|.||:|||...:||
Zfish   347 IADEIVAAFAELPQKVIWRYTGDRP--ANVGNNTLLVNWLPQNDLLGHPKTRVFVSHGGTNGVFE 409

  Fly   368 TVYHGVPVVTMPVFCDHDVNSAKAEVDGYAIKLDLQTLSANQLYKAIMKVIHNPRYRNSARHRQK 432
            .:|||||:|.:|:..|.|.|..|.:..|.|..||:.|::.|....|:.:|:::|.||::.:....
Zfish   410 AIYHGVPIVGLPLVFDQDYNLLKMKHKGVAKVLDIATINRNIFKDALQEVLNDPSYRSNMQKLSS 474

  Fly   433 LFLDQRSTALDTAIYWTEYVLRHNGAYHLQTPSRNMTWWQYYLLDVVAVYL--ILLYVLILALR 494
            |..|.....||:|::|||:|:||.||.||:|.|..|.|:.|:.:| |.|:|  :|.:::.|..:
Zfish   475 LHKDTPLKPLDSALFWTEFVMRHRGAAHLRTDSYKMPWYSYHSVD-VGVFLVSVLCFIVFLMFK 537

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt50B3	NP_001260710.1	YjiC	28..434	CDD:224732	122/441 (28%)
Ugt50B3	NP_001260710.1	egt	<172..479	CDD:223071	110/311 (35%)
ugt5f1	XP_017207383.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.810