DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt50B3 and ugt5d1

DIOPT Version :9

Sequence 1:	NP_001260710.1	Gene:	Ugt50B3 / 246614	FlyBaseID:	FBgn0050438	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_001170967.1	Gene:	ugt5d1 / 100415794	ZFINID:	ZDB-GENE-091118-36	Length:	532	Species:	Danio rerio

Alignment Length:	523	Identity:	147/523 - (28%)
Similarity:	240/523 - (45%)	Gaps:	62/523 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 IALFLIIWSCGTLAADILMATQGGTKSHKIPFWELAKGLISRGHNITFLSGFPADFNIEGLLEVT 69
            :||.....||.  ...||:....|  ||.:....|.:.|.||||:||.:....:.:..|.....|
Zfish    16 LALSAFTLSCS--GGKILLYPVDG--SHWVNMKVLIEELHSRGHSITVIRPKSSWYITEKSPLYT 76

  Fly    70 PAGLVEYIHNYTNW--DLLGSRMAGEMPIKPWDGLRYAF----------------ESCDAMLRDS 116
            ...:.:.::::.|:  |.|..    .|.|:..:|...||                .:|..:....
Zfish    77 SITIQDNVNDFENFFEDYLSK----AMEIERGEGSGLAFLKLQYDLFSMLSTAHEIACKMVSIIL 137

  Fly   117 ETKELTKK----SFDL-----AILDGAFPECFLGLMYDFKIPF-MYINTVGFYTGSISTAGNPVS 171
            |.|.|.||    .:||     ||..|.|      |.:..|:|. :.:..:....|..:.|.:|:|
Zfish   138 EDKMLVKKLQDEQYDLMLTDPAIAGGVF------LAHYLKLPLVLNVRWITSGEGHFAIAPSPMS 196

  Fly   172 YAITPNFYSRFTDTMNLYERAINTAMQIGQTLMHMYVMRRTHLVMREHLGTQIPHPYEMSRNVSF 236
            |...|.  |..||.|...:|..|       .|...:...:...|:..|....|....:...::..
Zfish   197 YIPLPG--SGHTDKMGFAQRVKN-------VLFKTFTFLQNRFVVGPHYDILIDKYLDYKTDIVG 252

  Fly   237 ILQ-------NGHAVLSYPRAFNPNVAEVACIHCRPARKLPRNLEEFIGASGASGFIYVSMGSSV 294
            ::|       ....|..:||...||:..:....|:|::.||.:||.|..:||..|||.:|:|:.|
Zfish   253 LIQAADIWLMRADFVFEFPRPTMPNIVYMGGFRCKPSKPLPADLEAFAQSSGEHGFIIMSLGTLV 317

  Fly   295 KAANMPEALRHMLVKTFARLPYHVLWKYEGSSTDIKDITSNVKLSRWLPQQDILGHPKLRAFVTH 359
            |  ::|..:.:.:...|||||..|:|::.|...  .::.:|..:..|:||.|:|||.|::|||.|
Zfish   318 K--SLPADMANAIAAAFARLPQKVIWRHLGDRP--SNVGNNTLIVDWMPQNDLLGHSKIKAFVAH 378

  Fly   360 GGLLSMFETVYHGVPVVTMPVFCDHDVNSAKAEVDGYAIKLDLQTLSANQLYKAIMKVIHNPRYR 424
            ||...:.|.::|||||:.:|:|.|...|..:.:..|....|.|..|:|....:|:.:.:::..|:
Zfish   379 GGTNGVQEAIFHGVPVLGVPLFFDQFDNLIRVQGKGAGKILKLSELNAEAFEQALRESLNDGSYK 443

  Fly   425 NSARHRQKLFLDQRSTALDTAIYWTEYVLRHNGAYHLQTPSRNMTWWQYYLLDVVAVYLILLYVL 489
            .:.:....|..||....|||||:|.|:|:||.||.||::....|.|:.|:.:||..|..|:..|.
Zfish   444 RNMQTLSTLHRDQPMRPLDTAIFWIEHVIRHKGATHLRSEFYKMPWYSYHSVDVFLVLFIVAAVC 508

  Fly   490 ILA 492
            :|:
Zfish   509 MLS 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt50B3	NP_001260710.1	YjiC	28..434	CDD:224732	115/440 (26%)
Ugt50B3	NP_001260710.1	egt	<172..479	CDD:223071	96/313 (31%)
ugt5d1	NP_001170967.1	UDPGT	28..527	CDD:278624	143/509 (28%)
ugt5d1	NP_001170967.1	egt	<267..506	CDD:223071	86/242 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.810