Protein Alignment Ugt50B3 and ugt1a6

DIOPT Version :10

• Sequence 1: NP_724417.3
• Gene: Ugt50B3 / 246614
• FlyBaseID: FBgn0050438
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_001107366.1
• Gene: ugt1a6 / 100135191
• XenbaseID: XB-GENE-5793241
• Length: 531
• Species: Xenopus tropicalis
• Alignment Length: 568
• Identity: 158/568 - (27%)
• Similarity: 244/568 - (42%)
• Gaps: 123/568 - (21%)

  Fly     8 FLIIWSCGTLAAD---ILMATQGGTKSHKIPFWELAKGLISRGHNI------------------- 50
            |.|:.:.|  .||   :|:..|.|  ||.:....|...|..|||.|
 Frog    16 FFILLALG--CADGGRLLVVPQDG--SHWLSMRVLVDRLAQRGHYIVVAIPEVNMLFKDLDNYKV 76

  Fly    51 -TFLSGFPADFNIEGLLEVTPAGLVEYIHNYTNWDLLGSRMAGEMPIKPW-----DGLRYAFESC 109
             ||.|.:..|             ::|......|.::...|:..| .|..|     :..::...:|
 Frog    77 KTFSSPYSKD-------------VLENRMRRMNQEIFVDRILTE-KITFWYESMSNATQWVVSAC 127

  Fly   110 DAMLRDSE-TKELTKKSFDLAILDGAFPECFLGLMYDFKIPFMYINTVGFYTGSI-------STA 166
            ...|::|. .:||.|:.||..:.|..|| |...:.....||     :|.|..|:|       |..
 Frog   128 QHFLQNSTLIRELEKEHFDAMLTDSVFP-CGEIVAEHLSIP-----SVSFMRGTIFGMDQIASQT 186

  Fly   167 GNPVSYAITPNFYSRFTDTMNLYERAINTAMQIGQTLMHMYVMRRTHLVMREHLGTQI-PHPY-- 228
            .:|.||  .|..::.:||.|:..:|..|       .|:|..          ||:...| .:||
 Frog   187 PSPPSY--VPRMFTVYTDNMSFSQRVKN-------FLIHSL----------EHIVCHIFYYPYAQ 232

  Fly   229 -------------EMSRNVSFILQNGHAVLSYPRAFNPNVAEVACIHCRPARKLPRNLEEFIGAS 280
                         .:....|..|.....|..:||...|||..:..|:|...:.||:..|:.:.:|
 Frog   233 MASDFLKKEVTAMSLFSRTSIWLMRYDFVFEFPRPIMPNVILIGGINCAKQKALPQEFEKLVKSS 297

  Fly   281 GASGFIYVSMGSSVK------AANMPEALRHMLVKTFARLPYHVLWKYEGSSTDIKDITSNVKLS 339
            |..||:..|.||.|.      |.::.||||:        :|..|.|:|.|.:.  .::..|..|.
 Frog   298 GEHGFVVFSFGSMVSEIPMNIAMDIAEALRY--------IPQKVFWRYTGKAP--PNLGDNTHLV 352

  Fly   340 RWLPQQDILGHPKLRAFVTHGGLLSMFETVYHGVPVVTMPVFCDHDVNSAKAEVDGYAIKLDLQT 404
            :||||.|:|.|||.|||:||.|...::|.:.:.||:|.:|:..|...|:.:.|..|..:.|::|.
 Frog   353 KWLPQNDLLAHPKARAFITHAGSHGVYEGICNAVPMVMLPLIGDQMDNAKRIESRGAGLILNVQN 417

  Fly   405 LSANQLYKAIMKVIHNPRYRNSARHRQKLFLDQRSTALDTAIYWTEYVLRHNGAYHLQTPSRNMT 469
            |..:.|..|:|.||.||.|:.:.:....|..|:....||.|::|.|:|::|.||.||:..:.::.
 Frog   418 LIPDDLSNAVMAVIDNPSYKENIQRLSSLHRDRPVQPLDLAVHWVEFVMKHKGAPHLRPAAHDLN 482

  Fly   470 WWQYYLLDVVAVYL-ILLYVLILALRRIDF-----------PYEKVRS 505
            |.||..|||:|..| :||..|.::|:...|           |..|.:|
 Frog   483 WIQYQSLDVMAFLLAVLLTTLFISLKCSTFACRCCCKRNTKPKRKTKS 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt50B3	NP_724417.3	Glycosyltransferase_GTB-type	43..480	CDD:471961	137/491 (28%)
ugt1a6	NP_001107366.1	UDPGT	28..527	CDD:278624	151/549 (28%)