DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG30429 and Als2

DIOPT Version :9

Sequence 1:NP_726512.1 Gene:CG30429 / 246609 FlyBaseID:FBgn0050429 Length:305 Species:Drosophila melanogaster
Sequence 2:NP_001153420.2 Gene:Als2 / 74018 MGIID:1921268 Length:1651 Species:Mus musculus


Alignment Length:217 Identity:57/217 - (26%)
Similarity:79/217 - (36%) Gaps:48/217 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    13 KPVCSSGRRATFYYP---GGGSYSGYWLCNKHQGWGVKKTAKRTCQYFYGKKHPEGQLIYEGDWV 74
            :|..|...:.|||..   ...:|.|.||..|..|.||             .|.|:|:: |.|.:.
Mouse  1021 EPPISRSAKYTFYKDTRLKDATYDGRWLSGKPHGRGV-------------LKWPDGKM-YSGMFR 1071

  Fly    75 MNKRQGVGS-MLRKRGTEVQLIYSGRWYDDMKCGEGKQFYSDGCVYFGKWIKNRRHGLGI----- 133
            .....|.|. .:..:....:..|.|.|.:...||:|...|:.|.|:.|.:..|.|||.|:     
Mouse  1072 NGLEDGYGEYRIPNKALNKEDHYVGHWKEGKMCGQGVYSYASGEVFEGCFQDNMRHGHGLLRSGK 1136

  Fly   134 -----------QWYND-------------GNIYAGEWETDFRHGLGVMFYANGNRYEGHFARGYK 174
                       ||..|             |..|.|.|:.|...|.||:....|..|||:|.....
Mouse  1137 LTSSSPSMFIGQWVMDKKAGYGVFDDITRGEKYMGMWQDDVCQGNGVVVTQFGLYYEGNFHLNKM 1201

  Fly   175 NGEGVFYHMHTGQIQKGMWEND 196
            .|.||.. .....|.:|.:.:|
Mouse  1202 MGNGVLL-SEDDTIYEGEFSDD 1222

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG30429NP_726512.1 COG4642 59..194 CDD:226989 43/164 (26%)
Als2NP_001153420.2 RCC1 1. /evidence=ECO:0000305 59..108
RCC1_2 93..122 CDD:290274
RCC1 2. /evidence=ECO:0000305 109..167
RCC1 109..165 CDD:278826
RCC1 3. /evidence=ECO:0000305 169..218
RCC1 170..216 CDD:278826
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 425..462
RCC1 4. /evidence=ECO:0000305 519..570
RCC1 521..568 CDD:278826
RCC1 5. /evidence=ECO:0000305 572..621
RCC1 573..619 CDD:278826
RhoGEF 689..873 CDD:295373
PH_alsin 899..1004 CDD:241423
PH 920..998 CDD:278594
COG4642 1043..1182 CDD:226989 39/152 (26%)
MORN 1 1043..1065 11/34 (32%)
MORN 1043..1063 CDD:280628 10/32 (31%)
MORN 2 1066..1088 4/21 (19%)
MORN 3 1094..1116 8/21 (38%)
MORN 1094..1114 CDD:280628 7/19 (37%)
MORN 4 1117..1139 6/21 (29%)
MORN 5 1145..1167 3/21 (14%)
COG4642 1166..>1266 CDD:226989 19/58 (33%)
MORN 6 1169..1191 8/21 (38%)
MORN 7 1192..1214 7/22 (32%)
MORN 8 1215..1238 2/8 (25%)
VPS9 1548..1647 CDD:280383
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG4642
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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