DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30429 and Jph2

DIOPT Version :9

Sequence 1:	NP_726512.1	Gene:	CG30429 / 246609	FlyBaseID:	FBgn0050429	Length:	305	Species:	Drosophila melanogaster
Sequence 2:	NP_001192005.1	Gene:	Jph2 / 59091	MGIID:	1891496	Length:	696	Species:	Mus musculus

Alignment Length:	241	Identity:	61/241 - (25%)
Similarity:	83/241 - (34%)	Gaps:	83/241 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 SSGRRATFYYPGGGSYSGYWLCNKHQGWGVKKTAKRTCQYFYGKKHPEGQLIYEGDWVMNKRQGV 81
            |.||   |.:..||:|.|.|...|..|.|:       |      ..|:||..|.|.|
Mouse     2 SGGR---FDFDDGGAYCGGWEGGKAHGHGL-------C------TGPKGQGEYSGSW-------- 42

  Fly    82 GSMLRKRGTEVQLIYSGRWYDDMKCGEGKQFYSDGCVYFGKWIKNRRHGLGIQ----WY------ 136
                 ..|.||..:|:               :..|..:.|.|.:.:||||||:    |.
Mouse    43 -----NFGFEVAGVYT---------------WPSGNTFEGYWSQGKRHGLGIETKGRWLYKGEWT 87

  Fly   137 -------------NDGNIYAGEWETDFRHGLGVMFYANGNRYEGHFARGYKNGEGVFYHMHTGQI 188
                         |.|..|.|.|....:.|.|...||:|..|:|.|..|.::|.||...:..|.
Mouse    88 HGFKGRYGIRQSTNSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGVRQSVPYGM- 151

  Fly   189 QKGMWENDNLKTS------------VVQDEPKIRCNAVITSYPIPR 222
              .:.....|:||            |..|.|... ..::.|.|:||
Mouse   152 --AVVVRSPLRTSLSSLRSEHSNGTVAPDSPAAD-GPMLPSPPVPR 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30429	NP_726512.1	COG4642	59..194	CDD:226989	38/157 (24%)
Jph2	NP_001192005.1	Bipartite nuclear localization signal. /evidence=ECO:0000269\|PubMed:30409805	345..359
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	439..664
		PHA03307	442..>643	CDD:223039
		Nuclear localization signal. /evidence=ECO:0000269\|PubMed:30409805	488..492
		PLN03185	4..>143	CDD:215619	47/182 (26%)
		MORN 1. /evidence=ECO:0000255	14..36		9/34 (26%)
		MORN 2. /evidence=ECO:0000255	38..59		8/48 (17%)
		MORN 3. /evidence=ECO:0000255	60..79		8/18 (44%)
		MORN 4. /evidence=ECO:0000255	82..104		1/21 (5%)
		PLN03185	103..>328	CDD:215619	27/96 (28%)
		MORN 5. /evidence=ECO:0000255	106..128		8/21 (38%)
		MORN 6. /evidence=ECO:0000255	129..151		7/21 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	164..192		4/28 (14%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	246..273
		MORN 7. /evidence=ECO:0000255	285..307
		MORN 8. /evidence=ECO:0000255	308..330
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4642
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900