DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30429 and JPH3

DIOPT Version :9

Sequence 1:	NP_726512.1	Gene:	CG30429 / 246609	FlyBaseID:	FBgn0050429	Length:	305	Species:	Drosophila melanogaster
Sequence 2:	NP_065706.2	Gene:	JPH3 / 57338	HGNCID:	14203	Length:	748	Species:	Homo sapiens

Alignment Length:	151	Identity:	50/151 - (33%)
Similarity:	64/151 - (42%)	Gaps:	19/151 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 SSGRRATFYYPGGGSYSGYWLCNKHQGWGVKKTAKRTCQYFYGKKH----------PEGQLIYEG 71
            |||.|  |.:..||||.|.|...|..|.||....|...:|.....|          |.|. .|:|
Human     2 SSGGR--FNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPSGN-TYQG 63

  Fly    72 DWVMNKRQGVGSMLRKRGTEVQLIYSGRWYDDMKCGEG-KQFYSDGCVYFGKWIKNRRHGLGIQW 135
            .|...||.|:|  |..:|   :.:|.|.|....|...| ::...:|..|.|.|....:.|.|.:.
Human    64 TWAQGKRHGIG--LESKG---KWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYGTET 123

  Fly   136 YNDGNIYAGEWETDFRHGLGV 156
            |:||..|.|:|....|.|.||
Human   124 YSDGGTYQGQWVGGMRQGYGV 144

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30429	NP_726512.1	COG4642	59..194	CDD:226989	33/109 (30%)
JPH3	NP_065706.2	MORN 1	15..37		8/21 (38%)
		MORN 2	39..60		4/21 (19%)
		MORN 3	61..82		9/25 (36%)
		MORN 4	83..105		5/21 (24%)
		MORN	107..129	CDD:280628	8/21 (38%)
		MORN 5	107..129		8/21 (38%)
		MORN 6	130..152		7/15 (47%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	230..259
		MORN 7	288..310
		MORN	311..333	CDD:280628
		MORN 8	311..333
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	416..496
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	526..597
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	624..649
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4642
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900