DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG30429 and Als2

DIOPT Version :9

Sequence 1:NP_726512.1 Gene:CG30429 / 246609 FlyBaseID:FBgn0050429 Length:305 Species:Drosophila melanogaster
Sequence 2:NP_001013431.1 Gene:Als2 / 363235 RGDID:1310372 Length:1651 Species:Rattus norvegicus


Alignment Length:228 Identity:59/228 - (25%)
Similarity:84/228 - (36%) Gaps:52/228 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 STCLERFFCPNKPVCSSGRRATFYYP---GGGSYSGYWLCNKHQGWGVKKTAKRTCQYFYGKKHP 63
            |:.::|    .:|..|...:.|||..   ...:|.|.||..|..|.||             .|.|
  Rat  1014 SSTVQR----QEPPISRSAKYTFYKDTRLKDATYDGRWLSGKPHGRGV-------------LKWP 1061

  Fly    64 EGQLIYEGDWVMNKRQGVGS-MLRKRGTEVQLIYSGRWYDDMKCGEGKQFYSDGCVYFGKWIKNR 127
            :|: :|.|.:......|.|. .:..:....:..|.|.|.:...||:|...|:.|.|:.|.:..|.
  Rat  1062 DGK-VYSGTFRNGLEDGYGEYRIPNKALNKEDHYVGHWKEGKMCGQGVYSYASGEVFEGCFQDNM 1125

  Fly   128 RHGLGI----------------QWYND-------------GNIYAGEWETDFRHGLGVMFYANGN 163
            |||.|:                ||..|             |..|.|.|:.|...|.||:....|.
  Rat  1126 RHGHGLLRSGKLTSSSPSMFIGQWVMDKKAGYGVFDDITRGEKYMGMWQDDACQGNGVVVTQFGL 1190

  Fly   164 RYEGHFARGYKNGEGVFYHMHTGQIQKGMWEND 196
            .|||:|......|.||.. .....|.:|.:.:|
  Rat  1191 YYEGNFHLNKMMGNGVLL-SEDDTIYEGEFSDD 1222

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG30429NP_726512.1 COG4642 59..194 CDD:226989 43/164 (26%)
Als2NP_001013431.1 RCC1 1 59..108
RCC1_2 93..122 CDD:290274
RCC1 2 109..167
RCC1 109..165 CDD:278826
RCC1 3 169..218
RCC1 170..216 CDD:278826
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 444..476
RCC1 4 519..570
RCC1 521..568 CDD:278826
RCC1 5 572..621
RCC1 573..619 CDD:278826
RhoGEF 689..873 CDD:295373
PH_alsin 899..1004 CDD:241423
PH 920..998 CDD:278594
COG4642 1043..1182 CDD:226989 39/152 (26%)
MORN 1 1043..1065 11/35 (31%)
MORN 1043..1063 CDD:280628 10/32 (31%)
MORN 2 1066..1088 4/21 (19%)
MORN 3 1094..1116 8/21 (38%)
MORN 1094..1114 CDD:280628 7/19 (37%)
MORN 4 1117..1139 6/21 (29%)
MORN 5 1145..1167 3/21 (14%)
COG4642 1166..>1266 CDD:226989 19/58 (33%)
MORN 6 1169..1191 8/21 (38%)
MORN 7 1192..1214 7/22 (32%)
MORN 8 1215..1238 2/8 (25%)
VPS9 1548..1647 CDD:280383
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG4642
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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