DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30429 and Als2cl

DIOPT Version :9

Sequence 1:	NP_726512.1	Gene:	CG30429 / 246609	FlyBaseID:	FBgn0050429	Length:	305	Species:	Drosophila melanogaster
Sequence 2:	NP_001139531.1	Gene:	Als2cl / 235633	MGIID:	2447532	Length:	952	Species:	Mus musculus

Alignment Length:	194	Identity:	46/194 - (23%)
Similarity:	65/194 - (33%)	Gaps:	58/194 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 KTAKRTCQYFYGKKH-------------PEGQLIYEGDWVMNKRQGVGSMLRKRGTEVQLIYSGR 99
            |..:..||...|||.             ||.:.             |....|:.|...|..|.|.
Mouse   310 KVTQAVCQALCGKKDFPVLGSGRETSVPPECRC-------------VAYTFRREGRLCQATYDGE 361

  Fly   100 WYDDMKCGEGKQFYSDGCVYFGKWIKNRRHGLGI----------------QW------------Y 136
            |......|:|...:.||..:.|.:.:...||.||                .|            |
Mouse   362 WCRAKPHGKGTLKWPDGRNHVGTFYQGLEHGFGICLVPQASEDKFDCYKCHWREGRMCEYGICEY 426

  Fly   137 NDGNIYAGEWETDFRHGLGVMFYA----NGNRYEGHFARGYKNGEGVFYHMHTGQIQKGMWEND 196
            ....:|.|.::...|||.|::..|    ...||.||:.||.::|.|:......|:...|||:.|
Mouse   427 GTDEVYKGYFQAGLRHGFGILESAPQAPQPFRYTGHWERGQRSGYGIEEDRDRGERYIGMWQAD 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30429	NP_726512.1	COG4642	59..194	CDD:226989	41/179 (23%)
Als2cl	NP_001139531.1	PH-like	223..321	CDD:388408	3/10 (30%)
		PLN03185	357..>550	CDD:215619	34/134 (25%)
		MORN 1	358..380		7/21 (33%)
		MORN 2	381..403		5/21 (24%)
		MORN 3	409..431		2/21 (10%)
		MORN 4	432..454		7/21 (33%)
		MORN 5	459..481		7/21 (33%)
		MORN 6	483..505		4/8 (50%)
		MORN 7	506..528
		MORN 8	529..552
		VPS9	835..937	CDD:388595
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4642
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900