DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30429 and Pms2

DIOPT Version :9

Sequence 1:	NP_726512.1	Gene:	CG30429 / 246609	FlyBaseID:	FBgn0050429	Length:	305	Species:	Drosophila melanogaster
Sequence 2:	XP_036020772.1	Gene:	Pms2 / 18861	MGIID:	104288	Length:	875	Species:	Mus musculus

Alignment Length:	213	Identity:	65/213 - (30%)
Similarity:	98/213 - (46%)	Gaps:	32/213 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 FCPNKPVCSSGRRATFYYPGGGSYSGYWLCNKHQGWGVKKTAKRTCQYF----YGKKHPEGQLI- 68
            |..|.|:    ....:.:|.|.:|.|........|:|:.|...:...|.    :||:|.:|.:.
Mouse   136 FVKNIPM----NHGVYTWPDGSTYEGEVTNGMRNGFGMFKCGTQPVSYIGHWCHGKRHGKGSIYY 196

  Fly    69 -------YEGDWVMNKRQGVGSMLRKRGTEVQLIYSGRWYDDMKCGEGK-QFYSDGCVYFGKWIK 125
                   ||||||.|.::|.|....|.|.    ||.|:|.::|:.|||: ::.:....|.|.|.|
Mouse   197 NQEGTSWYEGDWVYNIKKGWGIRCYKSGN----IYEGQWENNMRHGEGRMRWLTTNEEYTGHWEK 257

  Fly   126 NRRHGLGIQ-W---------YNDGNIYAGEWETDFRHGLGVMFYANGNRYEGHFARGYKNGEGVF 180
            ..::|.|.. |         |...|.|.||:...||||.|..:||:|..|||.:|...|.|.|..
Mouse   258 GIQNGFGTHTWFLKRIPNSQYPLRNEYIGEFVNGFRHGQGKFYYASGAMYEGEWASNKKQGRGRM 322

  Fly   181 YHMHTGQIQKGMWENDNL 198
             ....|.:.:|::.||::
Mouse   323 -TFKNGHVYEGLFSNDHI 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30429	NP_726512.1	COG4642	59..194	CDD:226989	52/153 (34%)
Pms2	XP_036020772.1	PLN03185	106..>405	CDD:215619	65/213 (31%)
Pms2	XP_036020772.1	vATP-synt_E	782..>829	CDD:419987
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4642
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1309439at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910