DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30424 and Cgas

DIOPT Version :9

Sequence 1:	NP_001097455.1	Gene:	CG30424 / 246606	FlyBaseID:	FBgn0050424	Length:	389	Species:	Drosophila melanogaster
Sequence 2:	XP_038938458.1	Gene:	Cgas / 682147	RGDID:	1586939	Length:	510	Species:	Rattus norvegicus

Alignment Length:	367	Identity:	83/367 - (22%)
Similarity:	139/367 - (37%)	Gaps:	119/367 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LKIAKPNEFDLVFKLKFP------YYKSIAVTR--DPKIP-GNVL--------LDMTRVLELLKD 49
            :||:.|||||::|||:.|      ||::.|..|  ..:|| ||.|        |..|:||
  Rat   207 VKISAPNEFDVMFKLEVPRIELEEYYETGAFYRVKFKRIPRGNPLSHFLEGEVLSATKVL----- 266

  Fly    50 DPREDFQRIRELIQGRLVDAQNFFVVDRLRSWLQSLFSQALNRISYRVELVAGVVSHLKYRTCGP 114
                  .:.||||:..:.:.::..|.                     ||         :.:...|
  Rat   267 ------SKFRELIKEEVKEIKDTDVT---------------------VE---------EEKPGSP 295

  Fly   115 AHTIYVYGDYEYSVDYVPAICLAAE---------------QNVLPTKQLECFKRANTSYWEAIPK 164
            |.|:.:....|.|||    |.||.|               |:.|.||.....:|   ..:..:||
  Rat   296 AVTLLIRNPEEISVD----IILALESKGSWPISTKGGLPIQDWLGTKVRTNLRR---EPFYLVPK 353

  Fly   165 PLKPLTETSMISFRSSFYAVEKILLQD--VHENC----------RNAIRFMK--------KFRDV 209
            ..|........::|.||...||.:|.:  :.:.|          :..::.||        :|:::
  Rat   354 NAKDGNRFQGETWRLSFSHTEKYILNNHGIGKTCCESSGAKCCRKECLKLMKYLLEQLKREFQEL 418

  Fly   210 KTNLGNCKSYYIKTLFLWKIIQEPESYWLNPLSFILADMFDD----LAENLRRGVITFFWDPELN 270
            .   ..| ||::||.......::|:....:|.:  |:..||.    ..|.||...:..::.|:.|
  Rat   419 D---AFC-SYHVKTAIFHMWTKDPQDSQWDPRN--LSTCFDKFLTFFLECLRTEKLDHYFIPKFN 477

  Fly   271 MIDALTRDQVWEMYLCVQRIPRDLRGAEISRNKWSFFVLREF 312
            :......|:..:.:|. ::|       |..||. .|.:..:|
  Rat   478 LFSQELIDKKSKEFLS-EKI-------EYERNN-GFPIFNKF 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30424	NP_001097455.1	Mab-21	1..289	CDD:281298	77/342 (23%)
Cgas	XP_038938458.1	PHA03247	<2..143	CDD:223021
Cgas	XP_038938458.1	Mab-21	203..498	CDD:397398	78/352 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D331478at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10656
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.110