DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30424 and Itprip

DIOPT Version :9

Sequence 1:	NP_001097455.1	Gene:	CG30424 / 246606	FlyBaseID:	FBgn0050424	Length:	389	Species:	Drosophila melanogaster
Sequence 2:	NP_001001738.2	Gene:	Itprip / 414801	MGIID:	3042776	Length:	555	Species:	Mus musculus

Alignment Length:	269	Identity:	52/269 - (19%)
Similarity:	97/269 - (36%)	Gaps:	62/269 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 IQGRLVDAQNFFV-VDRLRSWLQSLFSQALNRIS--YRVELVAGVVS-----HLKYRTCGPAHTI 118
            ::|.|...::.:: |.::..|.|...::|.:||:  |..:|..|.:.     .:|:|
Mouse   286 MEGLLCSRESSYLDVMQVMKWFQMALTRAWHRIAHKYEFDLAFGELDTPGSLKIKFR-------- 342

  Fly   119 YVYGDYEYSVDYVPAICLAAEQNVLPTKQLECFKRANTSYWEAIPKPLKPL--TETSMISFRSSF 181
                    |...:|.|.         |..::|   .::..:..:..|.:|.  ...|...:..||
Mouse   343 --------SGKSMPFIL---------TPVIQC---NDSDLYFILQLPKEPCGGGPASSAHWLLSF 387

  Fly   182 YAVEKILLQ---------DVHENCRNAIRFMKKFRDVKTNLGNCKSYYIKTLFLWKIIQEPESYW 237
            ...|:..|:         ..|.:|.....|:...:...|.......|::||..|..::....|.|
Mouse   388 AVYEREFLRMTGKALPEGACHLSCLQIASFLLSKQTRLTGPSGLSDYHLKTALLHLLLSRQASDW 452

  Fly   238 -LNPLSFILADMFDDLAENLRRGVITFFWDPELNMIDALTRDQVWEMYLCVQRIPRDLRGAEISR 301
             .:.|...|.|:|..|..:|....:..|:.....:.:||             .:|..:|.|| ..
Mouse   453 KASKLDVRLQDLFCFLERSLLEKKLYHFFMGNHKVPEAL-------------GLPEVVRRAE-PL 503

  Fly   302 NKWSFFVLR 310
            |.:..|||:
Mouse   504 NLFRPFVLQ 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30424	NP_001097455.1	Mab-21	1..289	CDD:281298	44/246 (18%)
Itprip	NP_001001738.2	Radial_spoke_3	<34..>67	CDD:399236
Itprip	NP_001001738.2	Mab-21	<377..485	CDD:397398	22/107 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838669
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930