Protein Alignment tbrd-3 and BRD2

DIOPT Version :9

• Sequence 1: NP_726307.1
• Gene: tbrd-3 / 246604
• FlyBaseID: FBgn0050417
• Length: 268
• Species: Drosophila melanogaster
• Sequence 2: NP_001186384.1
• Gene: BRD2 / 6046
• HGNCID: 1103
• Length: 836
• Species: Homo sapiens
• Alignment Length: 417
• Identity: 104/417 - (24%)
• Similarity: 148/417 - (35%)
• Gaps: 166/417 - (39%)

  Fly    11 SPEINACKVIIKRLFSSTYKNIAWVFYEPLDPQLLGLHDYHEIVREPMDLSTVRHRLNTGCYLSA 75
            |.::..|..|:|.|.|..:...||.||:|:|...|||||||:|::.|||||||:.::....|..|
Human   347 SEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDA 411

  Fly    76 ADFAKDIRLIFYNTYLYTNPDHLCYHMAKQLQIIFEEMYSQV--------QLYICS--------- 123
            .:||.|:||:|.|.|.|..|||....||::||.:||..|:::        .|.:.:
Human   412 QEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMPDEPLEPGPLPVSTAMPPGLAKS 476

  Fly   124 --------SGSKVRAEEESSSDESDSSSPEDEVNGSE---------------------------- 152
                    |.|:..:|||...||.|....|.|.:.||
Human   477 SSESSSEESSSESSSEEEEEEDEEDEEEEESESSDSEEERAHRLAELQEQLRAVHEQLAALSQGP 541

  Fly   153 ----------------------------------------------------------VSPSIMG 159
                                                                      :.||..|
Human   542 ISKPKRKREKKEKKKKRKAEKHRGRAGADEDDKGPRAPRPPQPKKSKKASGSGGGSAALGPSGFG 606

  Fly   160 ---------------------APP-------SC--TPTTE-------CTPTPDWTPPA-----TL 182
                                 .||       ||  .|:::       .|.|   .|||     ..
Human   607 PSGGSGTKLQAGVQWRDLGLLQPPLLGFKRFSCLSLPSSQDYRLPKKATKT---APPALPTGYDS 668

  Fly   183 ETSEQQEPFTTEEDLDLHAKIQQLDGEVLLHVIHFIQRMEGA--EYCNKELEFDICKLKVHTKRG 245
            |..|:..|.:.:|...|...|.:|.||.|..|:|.||..|.:  :...:|:|.|...||..|.|.
Human   669 EEEEESRPMSYDEKRQLSLDINKLPGEKLGRVVHIIQAREPSLRDSNPEEIEIDFETLKPSTLRE 733

  Fly   246 IRDYLAS-------KGFTGKR-VARTK 264
            :..|:.|       |.:|.|: |.:||
Human   734 LERYVLSCLRKKPRKPYTIKKPVGKTK 760

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tbrd-3	NP_726307.1	Bromo_Brdt_II_like	13..114	CDD:99930	46/100 (46%)
BRD2	NP_001186384.1	Bromo_Brdt_I_like	74..180	CDD:99929
		Bromo_Brdt_II_like	349..450	CDD:99930	46/100 (46%)
		GVQW	616..>651	CDD:290611	5/34 (15%)
		BET	676..740	CDD:293640	21/63 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000322
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22880
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X197
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	4.010