DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tbrd-3 and tbrd-1

DIOPT Version :9

Sequence 1:	NP_726307.1	Gene:	tbrd-3 / 246604	FlyBaseID:	FBgn0050417	Length:	268	Species:	Drosophila melanogaster
Sequence 2:	NP_001369030.1	Gene:	tbrd-1 / 42823	FlyBaseID:	FBgn0039124	Length:	513	Species:	Drosophila melanogaster

Alignment Length:	219	Identity:	56/219 - (25%)
Similarity:	90/219 - (41%)	Gaps:	48/219 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 IKRLFSSTYKN-IAWVFYEPLDPQLLGLHDYHEIVREPMDLSTVRHRLNTGCYLSAADFAKDIRL 84
            :|.:.:..::| .::.|..|:|...||:.|||.:|:.||||||:|.||:...|..|::..:|.:|
  Fly    47 LKSVLNCLWRNRFSYHFRHPVDSVSLGVPDYHAVVKHPMDLSTIRKRLHNKYYWQASEALEDFKL 111

  Fly    85 IFYNTYLYTNPDHLCYHMAKQLQIIFE------EMYSQVQLYICSSGSKVRAEEESSSDESDSSS 143
            ||.|..||.......|...|.|...|.      ::.::|:|...|...|.:|.|......:..|:
  Fly   112 IFDNCLLYNLEGSPVYQAGKLLMEAFYMRMESIDLSTEVELKPKSEKRKRKATESLDQASTSFSA 176

  Fly   144 PEDEVNGSE-----------------------------VSPSIMGAPPSCTPTTECTPTPDWTPP 179
            |....|.|.                             |.||::   ||..|.:...|.....|.
  Fly   177 PRASNNYSRQWLSSSSSWLCPPPMPGGVSSFNPSFRNFVGPSLI---PSFMPDSLVNPMQSMHPM 238

  Fly   180 ATL---------ETSEQQEPFTTE 194
            :::         ||:|..:|..:|
  Fly   239 SSMMNPIFKNNWETNEAMDPPPSE 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tbrd-3	NP_726307.1	Bromo_Brdt_II_like	13..114	CDD:99930	33/99 (33%)
tbrd-1	NP_001369030.1	Bromodomain	39..143	CDD:413371	33/95 (35%)
tbrd-1	NP_001369030.1	Bromodomain	328..423	CDD:413371
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468247
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000322
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22880
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.840