DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tbrd-3 and fs(1)h

DIOPT Version :9

Sequence 1:	NP_726307.1	Gene:	tbrd-3 / 246604	FlyBaseID:	FBgn0050417	Length:	268	Species:	Drosophila melanogaster
Sequence 2:	NP_001259321.1	Gene:	fs(1)h / 31722	FlyBaseID:	FBgn0004656	Length:	2046	Species:	Drosophila melanogaster

Alignment Length:	187	Identity:	65/187 - (34%)
Similarity:	94/187 - (50%)	Gaps:	38/187 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAAKQETERSSPEINACKVIIKRLFSSTYKNIAWVFYEPLDPQLLGLHDYHEIVREPMDLSTVRH 65
            :|..:..|:.|..:.:|..|:|.|||..:...||.||:|:|.::|||||||:|:::||||.||:.
  Fly   468 VAVAKNKEKLSDALKSCNEILKELFSKKHSGYAWPFYKPVDAEMLGLHDYHDIIKKPMDLGTVKR 532

  Fly    66 RLNTGCYLSAADFAKDIRLIFYNTYLYTNPDHLCYHMAKQLQIIFEEMYSQV------------- 117
            :::...|.||.:||.|:||||.|.|.|..|||....|.::||.:||..|:.:
  Fly   533 KMDNREYKSAPEFAADVRLIFTNCYKYNPPDHDVVAMGRKLQDVFEMRYANIPDEPVANAAHHHG 597

  Fly   118 ----------------------QLYICSSGSKVRAEEESSSDESDSSSPEDEVNGSE 152
                                  ..|..||..|..|.:.||.|.||:   |:|.|..|
  Fly   598 HGHGHGHGHGHGHGHGHGHGHGHGYGGSSSLKHDASDSSSEDSSDT---ENESNSDE 651

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tbrd-3	NP_726307.1	Bromo_Brdt_II_like	13..114	CDD:99930	47/100 (47%)
fs(1)h	NP_001259321.1	Bromo_Brdt_I_like	34..140	CDD:99929
		COG5076	387..>593	CDD:227408	51/124 (41%)
		Bromo_Brdt_II_like	481..581	CDD:99930	47/99 (47%)
		BET	951..1015	CDD:293640
		BRD4_CDT	<2026..2046	CDD:293710
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000322
OrthoInspector	1	1.000	-	-		mtm1066
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22880
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X197
	6	5.910