DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tbrd-3 and Pbrm1

DIOPT Version :9

Sequence 1:	NP_726307.1	Gene:	tbrd-3 / 246604	FlyBaseID:	FBgn0050417	Length:	268	Species:	Drosophila melanogaster
Sequence 2:	XP_006252748.1	Gene:	Pbrm1 / 306254	RGDID:	1565549	Length:	1726	Species:	Rattus norvegicus

Alignment Length:	154	Identity:	37/154 - (24%)
Similarity:	65/154 - (42%)	Gaps:	31/154 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 RLFSSTYKNIAWVFYEPLDPQLLGLHDYHEIVREPMDLSTVRHRLNTGCYLSAADFAKDIRLIFY 87
            ||.|..::.:         |..:...||:.|::||:||.|:..|:..|.|.|....||||.|:..
  Rat   223 RLISELFQKL---------PSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAK 278

  Fly    88 NTYLYTNPDHLCYHMAKQLQIIFEEMYSQVQLY-ICSSGSKVR-----AEEESSSDESDSSSPED 146
            |...|..|....:..|..::.||....::::.: :..|..::|     |....:....:.||.::
  Rat   279 NAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMTKSSLRIRTATNLAAARLTGPSHNKSSLDE 343

  Fly   147 EVNGSEVSPSIMGAPPSCTPTTEC 170
            |.|                ||::|
  Rat   344 ERN----------------PTSKC 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tbrd-3	NP_726307.1	Bromo_Brdt_II_like	13..114	CDD:99930	27/90 (30%)
Pbrm1	XP_006252748.1	Bromo_polybromo_I	65..177	CDD:99954
		Bromo_polybromo_II	203..305	CDD:99948	27/90 (30%)
		Bromo_polybromo_III	404..505	CDD:99951
		Bromo_polybromo_IV	556..659	CDD:99949
		Bromo_polybromo_V	695..799	CDD:99946
		Bromo_polybromo_VI	812..919	CDD:99956
		BAH_polybromo	994..1111	CDD:240068
		BAH_polybromo	1192..1310	CDD:240068
		HMG-box	1417..1481	CDD:238037
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900