DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tbrd-3 and Brdt

DIOPT Version :9

Sequence 1:	NP_726307.1	Gene:	tbrd-3 / 246604	FlyBaseID:	FBgn0050417	Length:	268	Species:	Drosophila melanogaster
Sequence 2:	NP_001012031.1	Gene:	Brdt / 305123	RGDID:	1306678	Length:	326	Species:	Rattus norvegicus

Alignment Length:	258	Identity:	66/258 - (25%)
Similarity:	110/258 - (42%)	Gaps:	46/258 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 KVIIKRLFSSTYKNIAWVFYEPLDPQLLGLHDYHEIVREPMDLSTVRHRLNTGCYLSAADFAKDI 82
            :|::|.|:..::   :|.|.:|:|...|.|.||:.|:..||||||::.||....|..|::...|.
  Rat    36 RVVLKALWKHSF---SWPFQQPVDAAKLKLPDYYTIIETPMDLSTIKKRLENRYYEKASECVGDF 97

  Fly    83 RLIFYNTYLYTNPDHLCYHMAKQLQIIFEEMYSQVQLYICSSGSKVRAEEE--------SSSDES 139
            ..:|.|.|||..|......||:.|:.:|.:..||:.......|.|.|.:::        |:.:::
  Rat    98 NTMFSNCYLYNKPGDDIVVMAQALEKLFMQKLSQMPQEEQIVGGKERMKKDIQQKTAVSSAKEQT 162

  Fly   140 DSSSPEDEVNGSEV---------SPSIMG--APPSC-------------------TPTTECTPTP 174
            .|.|.|:.....|:         ||..|.  |||:|                   ||||......
  Rat   163 PSKSAENVFKRQEIPAGFPDVCLSPLNMAQEAPPTCDSQTVVQITKGVKRRADTTTPTTSSAKAS 227

  Fly   175 DWTPPATLETSEQQEPFTTEEDLDLHAKIQQLDGEVLLHVIHFIQRMEGAEYCNKELEFDICK 237
            ..:||...|......|  .:|:.   .|....|.:....|:..::..|..::|::.|:..:.|
  Rat   228 SESPPPLREAKPANAP--VKENT---VKSVLPDSQQQHRVLKTVKVTEQLKHCSEILKEMLAK 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tbrd-3	NP_726307.1	Bromo_Brdt_II_like	13..114	CDD:99930	33/95 (35%)
Brdt	NP_001012031.1	Bromo_Brdt_I_like	26..132	CDD:99929	34/98 (35%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	141..168		5/26 (19%)
		Nuclear localization signal. /evidence=ECO:0000250\|UniProtKB:Q58F21	208..219		0/10 (0%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	209..257		11/52 (21%)
		Bromodomain	271..>322	CDD:295360	3/15 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000322
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22880
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X197
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.010