DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tbrd-3 and BAZ2B

DIOPT Version :9

Sequence 1:	NP_726307.1	Gene:	tbrd-3 / 246604	FlyBaseID:	FBgn0050417	Length:	268	Species:	Drosophila melanogaster
Sequence 2:	XP_024308593.1	Gene:	BAZ2B / 29994	HGNCID:	963	Length:	2259	Species:	Homo sapiens

Alignment Length:	155	Identity:	37/155 - (23%)
Similarity:	76/155 - (49%)	Gaps:	13/155 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 AKQETERS--------SPEINACKVIIKRLFSSTYKNIAWVFYEPLDPQLLGLHDYHEIVREPMD 59
            :|||:..|        |.::..|.:|:..:  .|::: ||.|..|::.:|  :..|.:::::|||
Human  2110 SKQESFTSVKKPKRDDSKDLALCSMILTEM--ETHED-AWPFLLPVNLKL--VPGYKKVIKKPMD 2169

  Fly    60 LSTVRHRLNTGCYLSAADFAKDIRLIFYNTYLYTNPDHLCYHMAKQLQIIFEEMYSQVQLYICSS 124
            .||:|.:|::|.|.:...||.|:||:|.|...:...|.........::..||:.::.....:|..
Human  2170 FSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKKWTDTFKPLCYE 2234

  Fly   125 GSKVRAEEESSSDESDSSSPEDEVN 149
            .:.......:::.....:||..|.:
Human  2235 DALAAQPYGAANSYHQLTSPVPEAS 2259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tbrd-3	NP_726307.1	Bromo_Brdt_II_like	13..114	CDD:99930	28/100 (28%)
BAZ2B	XP_024308593.1	Nucleoporin_FG2	42..>226	CDD:330420
		HAT_MBD	761..833	CDD:238691
		TPH	903..>1089	CDD:316391
		DDT	1117..1179	CDD:214726
		WSD	1400..>1432	CDD:317927
		WSD	<1740..1779	CDD:317927
		PHD_BAZ2B	1995..2043	CDD:277100
		Bromo_BAZ2A_B_like	2128..2224	CDD:99935	28/100 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810