DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rpi and Rpia

DIOPT Version :9

Sequence 1:	NP_001246480.1	Gene:	Rpi / 246599	FlyBaseID:	FBgn0050410	Length:	241	Species:	Drosophila melanogaster
Sequence 2:	NP_033101.2	Gene:	Rpia / 19895	MGIID:	103254	Length:	303	Species:	Mus musculus

Alignment Length:	235	Identity:	142/235 - (60%)
Similarity:	181/235 - (77%)	Gaps:	5/235 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 DAAKKTAARTAVDQWVTEDTKILGIGSGSTVVYAVQRIAERVWKEGELTDLICVPSSYQARHLIL 71
            :.|||.|:.|||:..| ::.::||||||||:|:|||||||||.:|.  .||||:|:|:|||.|||
Mouse    72 EEAKKLASHTAVENHV-KNNQVLGIGSGSTIVHAVQRIAERVKQEN--LDLICIPTSFQARQLIL 133

  Fly    72 DYNLNLGDLDRNPNIDVAIDGADEVDRHMVLIKGGGGCLLQEKVVASCAKHFIVVADYTKNSIRL 136
            .|.|.|.|||::|.||:|||||||||..:.|||||||||.|||:||..|..|||:||:.|:|..|
Mouse   134 QYGLTLSDLDQHPEIDLAIDGADEVDAELNLIKGGGGCLTQEKIVAGYASRFIVIADFRKDSKNL 198

  Fly   137 GEQWCRGVPIEVAPMAYVPIKLHIEALFGGEASLRMAKVKAGPIVTDNGNFLLDWKFIANREYDW 201
            |::|.:|:||||.||||||:...:...||||..||||..||||:|||||||:|||||  :|.:.|
Mouse   199 GDRWHKGIPIEVIPMAYVPVSRAVAQKFGGEVELRMAVNKAGPVVTDNGNFILDWKF--DRVHKW 261

  Fly   202 DEVNRAITLIPGVLETGLFVNMAHKCYYGMANGSVKVQNK 241
            .|||.||.:.|||::||||:|||.:.|:||.:|||.|:.|
Mouse   262 SEVNTAIKMTPGVVDTGLFINMAERVYFGMQDGSVNVREK 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpi	NP_001246480.1	RPI_A	24..231	CDD:238692	127/206 (62%)
Rpia	NP_033101.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	22..75		0/2 (0%)
Rpia	NP_033101.2	RPI_A	74..291	CDD:238692	135/221 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849161
Domainoid	1	1.000	232	1.000	Domainoid score	I2415
eggNOG	1	0.900	-	-		E1_COG0120
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6943
Inparanoid	1	1.050	285	1.000	Inparanoid score	I2837
Isobase	1	0.950	-	0	Normalized mean entropy	S585
OMA	1	1.010	-	-		QHG60821
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002439
OrthoInspector	1	1.000	-	-		oto94859
orthoMCL	1	0.900	-	-		OOG6_101105
Panther	1	1.100	-	-	LDO	PTHR11934
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1198
SonicParanoid	1	1.000	-	-		X1856
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.740