DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30398 and Mitd1

DIOPT Version :9

Sequence 1:	NP_726113.1	Gene:	CG30398 / 246591	FlyBaseID:	FBgn0050398	Length:	267	Species:	Drosophila melanogaster
Sequence 2:	NP_001009714.1	Gene:	Mitd1 / 363219	RGDID:	1307700	Length:	249	Species:	Rattus norvegicus

Alignment Length:	225	Identity:	72/225 - (32%)
Similarity:	113/225 - (50%)	Gaps:	13/225 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 ALKCEQTGHIMEAILLYEESIFKLSQM--ADAEPSRRQLCGKYLKMYEARAKQLR---DQVK--G 81
            |::.:......:|::.|:|.|..|.|:  ...|.|:|......:..|..||:.::   ||.|  |
  Rat    22 AVELDAESRYQQALVCYQEGIDMLLQVLKGTKESSKRSTLRTKISGYMDRAENIKKYLDQEKEDG 86

  Fly    82 HLHTSRMLDHITIEQGARGRSYQRLFGPYLDDAVREAHLNEPHLTEPPHFRNLLNFFEVLVKN-C 145
            ..|     ..|.||:.|.|.||:.||..||.:.|.|..:.:|::.:.....|.|.|.|:|:|. |
  Rat    87 KYH-----KQIKIEENATGFSYESLFREYLQETVTEVWIEDPYIRQTHQLYNFLRFCEMLIKKPC 146

  Fly   146 RYLKYIRLTTRPDATAPKNQLQMLQQMQSDLAGGNIQMNFQMDDSLHDRKIVLSSGVVIKIGRGL 210
            :......||:..:......|...|::::..|....:.:......|:|||:|..::|.:|||||||
  Rat   147 KVRTIHLLTSGDEGFGNTQQSSGLEEIKQSLRSHGVVLEINYSSSIHDREIRFNNGWMIKIGRGL 211

  Fly   211 HYFEPMEGSYSLGLCDFDFRKCLATEVDIW 240
            .||:..:|.:|||.||.|.|.|..|.|||:
  Rat   212 DYFKKPQGRFSLGYCDLDLRPCHETTVDIF 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30398	NP_726113.1	MIT	13..83	CDD:294211	17/65 (26%)
CG30398	NP_726113.1	MIT_C	97..244	CDD:239148	51/145 (35%)
Mitd1	NP_001009714.1	MIT_1	10..86	CDD:239146	16/63 (25%)
		MIT_C	97..245	CDD:239148	51/145 (35%)
		Important for association with membranes. /evidence=ECO:0000250	168..231		24/62 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340792
Domainoid	1	1.000	104	1.000	Domainoid score	I6556
eggNOG	1	0.900	-	-		E1_KOG4509
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	158	1.000	Inparanoid score	I4175
OMA	1	1.010	-	-		QHG48951
OrthoDB	1	1.010	-	-		D1494805at2759
OrthoFinder	1	1.000	-	-		FOG0006049
OrthoInspector	1	1.000	-	-		otm46030
orthoMCL	1	0.900	-	-		OOG6_106548
Panther	1	1.100	-	-	O	PTHR21222
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4343
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.770