Protein Alignment Prosalpha1R and PSMB1

DIOPT Version :10

• Sequence 1: NP_724616.1
• Gene: Prosalpha1R / 246582
• FlyBaseID: FBgn0050382
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_002784.1
• Gene: PSMB1 / 5689
• HGNCID: 9537
• Length: 241
• Species: Homo sapiens
• Alignment Length: 244
• Identity: 50/244 - (20%)
• Similarity: 95/244 - (38%)
• Gaps: 54/244 - (22%)

  Fly     4 GSSAGFDRHITI------FSPEGRLYQVEYAFKAIAQENITTVALKSGDCAVVATQKKVTEK-NI 61
            |...|.:.|...      |||        |.|     ...|.:|:...|.|:||:..:::|. :|
Human    12 GRDLGMEPHRAAGPLQLRFSP--------YVF-----NGGTILAIAGEDFAIVASDTRLSEGFSI 63

  Fly    62 VPETVTHLFRITKD--IGCAMTGRIAD--SRSQVQKARYEAANFRYKYGYEMPVDVLCRRIADIN 122
            ........:::|..  |||  :|...|  :.:::.:||.:.  :::.....|....:...::.|
Human    64 HTRDSPKCYKLTDKTVIGC--SGFHGDCLTLTKIIEARLKM--YKHSNNKAMTTGAIAAMLSTI- 123

  Fly   123 QVYTQNAEMRPLGCSMVLIAYDNEIGPSVYKTDPAGYF--SGFKA-------------CSVGAKT 172
             :|::  ...|.....::...|.|...:||..||.|.:  ..|||             ..||.|.
Human   124 -LYSR--RFFPYYVYNIIGGLDEEGKGAVYSFDPVGSYQRDSFKAGGSASAMLQPLLDNQVGFKN 185

  Fly   173 LEANSYLEKKYKPNLSEEKAIQLAISCLSSVLAID-FKPNGIEIGVVSK 220
            ::...::.      ||.::|::|......|....| :..:.:.|.:|:|
Human   186 MQNVEHVP------LSLDRAMRLVKDVFISAAERDVYTGDALRICIVTK 228

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha1R	NP_724616.1	proteasome_alpha_type_6	8..218	CDD:239723	47/236 (20%)
PSMB1	NP_002784.1	proteasome_beta_type_1	30..241	CDD:239726	47/226 (21%)