Protein Alignment Prosalpha1R and PSMA7

DIOPT Version :10

• Sequence 1: NP_724616.1
• Gene: Prosalpha1R / 246582
• FlyBaseID: FBgn0050382
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_002783.1
• Gene: PSMA7 / 5688
• HGNCID: 9536
• Length: 248
• Species: Homo sapiens
• Alignment Length: 238
• Identity: 77/238 - (32%)
• Similarity: 131/238 - (55%)
• Gaps: 7/238 - (2%)

  Fly     9 FDRHITIFSPEGRLYQVEYAFKAIAQENITTVALKSGDCAVVATQKKVTEKNIVPETVTHLFRIT 73
            :||.||:|||:|.|:|||||.:|: ::..|.|.::..|..|:..:||...|.....||..:..:.
Human     3 YDRAITVFSPDGHLFQVEYAQEAV-KKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVRKICALD 66

  Fly    74 KDIGCAMTGRIADSRSQVQKARYEAANFRYKYGYEMPVDVLCRRIADINQVYTQNAEMRPLGCSM 138
            .::..|..|..||:|..:.:||.|..:.|......:.|:.:.|.||.:.|.|||:...||.|.|.
Human    67 DNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISA 131

  Fly   139 VLIAYDNEIGPSVYKTDPAGYFSGFKACSVGAKTLEANSYLEKKYKPNL--SEEKAIQLAISCLS 201
            :::.:|.:..|.:|:|||:|.:..:||.::|........:|||.|....  :::..|:|.|..|.
Human   132 LIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDEAIETDDLTIKLVIKALL 196

  Fly   202 SVLAIDFKPNGIEIGVVSKSDPTFRILDEREIEEHLTKIAEKD 244
            .|:....|  .||:.|: :.|.:.:||:..|||:::.:| ||:
Human   197 EVVQSGGK--NIELAVM-RRDQSLKILNPEEIEKYVAEI-EKE 235

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha1R	NP_724616.1	proteasome_alpha_type_6	8..218	CDD:239723	67/210 (32%)
PSMA7	NP_002783.1	proteasome_alpha_type_7	3..211	CDD:239724	67/210 (32%)