Protein Alignment Prosalpha1R and PSMA3

DIOPT Version :10

• Sequence 1: NP_724616.1
• Gene: Prosalpha1R / 246582
• FlyBaseID: FBgn0050382
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_002779.1
• Gene: PSMA3 / 5684
• HGNCID: 9532
• Length: 255
• Species: Homo sapiens
• Alignment Length: 258
• Identity: 77/258 - (29%)
• Similarity: 123/258 - (47%)
• Gaps: 37/258 - (14%)

  Fly     8 GFDRHITIFSPEGRLYQVEYAFKAIAQENITTVALKSGDCAVVATQKKVTEKNIVPETVTHLFRI 72
            |:|...:.|||:||::|||||.||: :.:.|.:.::..|..|...:|.|..|.....:...||.:
Human     7 GYDLSASTFSPDGRVFQVEYAMKAV-ENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRLFNV 70

  Fly    73 TKDIGCAMTGRIADSRSQVQKARYEAANFRYKYGYEMPVDVLCRRIADINQVYTQNAEMRPLGCS 137
            .:.:|.|:.|.:||:||....||.||:|||..:||.:|:..|..|:|.....||..:.:||.|||
Human    71 DRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYSAVRPFGCS 135

  Fly   138 MVLIAYDNEIGPSVYKTDPAGYFSGFKACSVGAKTLEANSYLEKKYKPNLS-------------- 188
            .:|.:|....|..:|..||:|...|:..|::|.....|.:.:||.....::
Human   136 FMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEMTCRDIVKEVAKIIYI 200

  Fly   189 -----EEKAIQLAISCLSSVLAIDFKPNGIEIGVVSKSDPTFRILDEREIEEHLTK--IAEKD 244
                 ::||.:|.:|.:..:      .|| ...:|.|        |.||..|...|  :.|:|
Human   201 VHDEVKDKAFELELSWVGEL------TNG-RHEIVPK--------DIREEAEKYAKESLKEED 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha1R	NP_724616.1	proteasome_alpha_type_6	8..218	CDD:239723	68/228 (30%)
PSMA3	NP_002779.1	proteasome_alpha_type_3	5..217	CDD:239720	66/210 (31%)