Protein Alignment Prosalpha1R and PSMA8

DIOPT Version :10

• Sequence 1: NP_724616.1
• Gene: Prosalpha1R / 246582
• FlyBaseID: FBgn0050382
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_653263.2
• Gene: PSMA8 / 143471
• HGNCID: 22985
• Length: 256
• Species: Homo sapiens
• Alignment Length: 246
• Identity: 78/246 - (31%)
• Similarity: 134/246 - (54%)
• Gaps: 17/246 - (6%)

  Fly     9 FDRHITIFSPEGRLYQVEYAFKAIAQENITTVALKSGDCAVVATQKKVTEKNIVPETVTHLFRIT 73
            :||.||:|||:|.|:|||||.:|: ::..|.|.::..:..|:..:||...|.....||..:..:.
Human     5 YDRAITVFSPDGHLFQVEYAQEAV-KKGSTAVGIRGTNIVVLGVEKKSVAKLQDERTVRKICALD 68

  Fly    74 KDIGCAMT------GRIADSRSQVQKARYEAANFRYKYGYEMPVDV--LCRRIADINQVYTQNAE 130
            ..:..|..      |..||:|..:.:||.|..:  :|...|.||.|  :.|.||.:.|.|||:..
Human    69 DHVCMAFAVLTIFIGLTADARVVINRARVECQS--HKLTVEDPVTVEYITRFIATLKQKYTQSNG 131

  Fly   131 MRPLGCSMVLIAYDNEIGPSVYKTDPAGYFSGFKACSVGAKTLEANSYLEKKYKPN--LSEEKAI 193
            .||.|.|.:::.:|::....:|:|||:|.:..:||.::|........:|||.|..:  .|:.:||
Human   132 RRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYTEDAIASDSEAI 196

  Fly   194 QLAISCLSSVLAIDFKPNGIEIGVVSKSDPTFRILDEREIEEHLTKIAEKD 244
            :|||..|..|:....|  .||:.::.::.| .::...:|:|.::|:| ||:
Human   197 KLAIKALLEVVQSGGK--NIELAIIRRNQP-LKMFSAKEVELYVTEI-EKE 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha1R	NP_724616.1	proteasome_alpha_type_6	8..218	CDD:239723	71/218 (33%)
PSMA8	NP_653263.2	proteasome_alpha_type_7	5..219	CDD:239724	71/218 (33%)