DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE9 and CLIC5

DIOPT Version :9

Sequence 1:	NP_725784.1	Gene:	GstE9 / 246581	FlyBaseID:	FBgn0063491	Length:	221	Species:	Drosophila melanogaster
Sequence 2:	NP_001107558.1	Gene:	CLIC5 / 53405	HGNCID:	13517	Length:	410	Species:	Homo sapiens

Alignment Length:	171	Identity:	36/171 - (21%)
Similarity:	61/171 - (35%)	Gaps:	41/171 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 NLLAGEHKTKEFSLKN--PQHTVPVLEDDGKFIWESHAICAYLVRRYAKSDDLYPKDYFKRALVD 97
            |:...:.|.|...|.|  |....|.|..:|....:.:.|..:|      .:.|.|:.|.|.|
Human   209 NVTTVDLKRKPADLHNLAPGTHPPFLTFNGDVKTDVNKIEEFL------EETLTPEKYPKLA--- 264

  Fly    98 QRLHFESGVL-------FQGCIRNIAIPLFYKNITEVPRSQIDAIYEAYDFLEAFI--------- 146
             ..|.||...       |...|:|..    .:|...:.|....|:.:..|:|...:
Human   265 -AKHRESNTAGIDIFSKFSAYIKNTK----QQNNAALERGLTKALKKLDDYLNTPLPEEIDANTC 324

  Fly   147 -----GNQAYLCGPVITIADYSVVSSVSSLVGLAAIDAKRY 182
                 ..:.:|.|..:|:||.:::..:.    :..|.||:|
Human   325 GEDKGSRRKFLDGDELTLADCNLLPKLH----VVKIVAKKY 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE9	NP_725784.1	GstA	4..201	CDD:223698	36/171 (21%)
		GST_N_Delta_Epsilon	4..76	CDD:239343	10/42 (24%)
		GST_C_Delta_Epsilon	92..209	CDD:198287	22/112 (20%)
CLIC5	NP_001107558.1	O-ClC	173..408	CDD:129941	36/171 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154557
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930