DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE9 and gst2

DIOPT Version :9

Sequence 1:	NP_725784.1	Gene:	GstE9 / 246581	FlyBaseID:	FBgn0063491	Length:	221	Species:	Drosophila melanogaster
Sequence 2:	NP_588517.1	Gene:	gst2 / 2539601	PomBaseID:	SPCC965.07c	Length:	230	Species:	Schizosaccharomyces pombe

Alignment Length:	224	Identity:	67/224 - (29%)
Similarity:	88/224 - (39%)	Gaps:	38/224 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGKLVLYGVEASPPVRACKLTLDALGLQYEYRLVNLLAGEHKTKEFSLKNPQHTVPVLED---DG 62
            |....||.....|......|.|..|.|.||....:...||.|.||....||...||.|.|   :.
pombe     1 MAHFTLYSHAGGPNPWKVVLALKELNLSYEQIFYDFQKGEQKCKEHLALNPNGRVPTLVDHKNND 65

  Fly    63 KFIWESHAICAYLVRRY-------AKSDDLYPKDYFKRALVDQRLHFE-SGVLFQGCIRNIA--I 117
            ..||||.||..||..:|       ...||   .:|:|   :.|.|.|: ||   ||.|...|  .
pombe    66 YTIWESDAILIYLADKYDTDRKISLSFDD---PEYYK---LIQYLFFQASG---QGVIWGQAGWF 121

  Fly   118 PLFYKN--ITEVPRSQIDAIYEAYDFLEAFIGNQAYLCGPVITIADYSVVSSVSSLVGL------ 174
            ..|:..  ::.|.|.: :.|......||..:.::.||.....||||.|.:....:|.||
pombe   122 NFFHHEPVVSAVTRYR-NEIKRVLGVLEDILKDRDYLVANKYTIADLSFIPWNYNLGGLFGEGKF 185

  Fly   175 ------AAID-AKRYPKLNGWLDRMAAQP 196
                  ..:| .|.:||...|..|:.|:|
pombe   186 SFKEEVPQLDFEKEFPKAYAWNQRLLARP 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE9	NP_725784.1	GstA	4..201	CDD:223698	66/221 (30%)
		GST_N_Delta_Epsilon	4..76	CDD:239343	27/74 (36%)
		GST_C_Delta_Epsilon	92..209	CDD:198287	34/123 (28%)
gst2	NP_588517.1	GST_N_Ure2p_like	4..84	CDD:239346	29/79 (37%)
		GstA	5..226	CDD:223698	66/220 (30%)
		GST_C_Ure2p	96..219	CDD:198326	35/126 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	54	1.000	Domainoid score	I3221
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	80	1.000	Inparanoid score	I1854
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm9258
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
TreeFam	0	0.000	Not matched by this tool.
	8	7.860